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A new interesting article has been published in mBio. 2020 Mar 20; 11(2). pii: e00398-20. doi: 10.1128/mBio.00398-20. and titled:

Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection.

Authors of this article are:

Fedson DS, Opal SM, Rordam OM.

A summary of the article is shown below:

Patients with COVID-19 infection are at risk of acute respiratory disease syndrome (ARDS) and death. The tissue receptor for COVID-19 is ACE2, and higher levels of ACE2 can protect against ARDS. Angiotensin receptor blockers and statins upregulate ACE2. Clinical trials are needed to determine whether this drug combination might be used to treat patients with severe COVID-19 infection.Copyright © 2020 Fedson et al.

Check out the article’s website on Pubmed for more information:

This article is a good source of information and a good way to become familiar with topics such as: Angiotensin II Type 2 Receptor Blockers; Coronavirus Infections; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Peptidyl-Dipeptidase A; Pneumonia, Viral; Receptor, Angiotensin, Type 2; Receptors, Virus.

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