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Aprotinin from Bovine Lung (Lyophilized powder)

$275.00 $150.00

Catalog # P2010003 – 50 mg

Aprotinin is a small protein that acts as an inhibitor of the protease trypsin. Aprotinin is used in protein purification to inhibit unwanted proteolytic activities (trypsin, chymotrypsin, elastase and the like). Size: 50 mg.

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SKU: P2010003 Category:

Description

Aprotinin from Bovine Lung.

Product Data Sheet
Catalog # P2010003
Size 50 mg
Molecular Weight 6.5 kDa
Other names Pancreatic Trypsin Inhibitor, Basic Protease Inhibitor, BPI, BPTI
Specific Activity 5 TIU/mg
Total Activity 250 TIU
Storage -20°C. Avoid repeated freeze/thaw cycles.
Supplied as White lyophilized powder (50 mg).
Application Protein purification
Keywords Aprotinin is a small protein that acts as an inhibitor of the protease trypsin. Aprotinin is used in protein purification to inhibit unwanted proteolytic activities (trypsin, chymotrypsin, elastase and the like).

 

References

  • Evidence-based review of the role of  in blood conservation during orthopaedic surgery. Kokoszka A, Kuflik P, Bitan F, Casden A, Neuwirth M. J Bone Joint Surg Am. 2005 May;87(5):1129-36.
  • The serine antiprotease aprotinin (Trasylol): a novel approach to reducing postoperative bleeding. Royston D. Blood Coagul Fibrinolysis. 1990 Mar-Apr;1(1):55-69.
  • Is aprotinin safe to use in a cohort at increased risk for thrombotic events: results from a randomized, prospective trial in off-pump coronary artery bypass. Grant MC, Kon Z, Joshi A, Christenson E, Kallam S, Burris N, Gu J, Poston RS. Ann Thorac Surg. 2008 Sep;86(3):815-22; discussion 815-22.
  • Aprotinin preserves hemostasis in aspirin-treated patients undergoing cardiopulmonary bypass. Tabuchi N, Huet RC, Sturk A, Eijsman L, Wildevuur CR. Ann Thorac Surg. 1994 Oct;58(4):1036-9.
  • Does preserve platelets in children with acyanogenic congenital heart disease undergone surgery with cardiopulmonary bypass? Ferreira CA, Vicente WV, Evora PR, Rodrigues AJ, Klamt JG, Carlotti AP, Carmona F, Manso PH. Rev Bras Cir Cardiovasc. 2009 Jul-Sep;24(3):373-81.
  • Low-dose  in internal mammary artery bypass operations contributes to important blood saving. Schönberger JP, Everts PA, Ercan H, Bredée JJ, Bavinck JH, Berreklouw E, Wildevuur CR. Ann Thorac Surg. 1992 Dec;54(6):1172-6.
  • Engineering sugarcane cultivars with bovine pancreatic trypsin inhibitorgene for protection against top borer (Scirpophaga excerptalis Walker). Christy LA, Arvinth S, Saravanakumar M, Kanchana M, Mukunthan N, Srikanth J, Thomas G, Subramonian N. Plant Cell Rep. 2009 Feb;28(2):175-84.

Material Safety Data Sheet

References

1- Hewlett G. Apropos aprotinin: a review. Biotechnology (N Y). 1990 Jun;8(6):565-6, 568.

2- D’Ambra MN, Risk SC. Aprotinin, erythropoietin, and blood substitutes. Int Anesthesiol Clin. 1990 Fall;28(4):237-40.