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Crystallization Screen for Protein-DNA Complexes

$795.00 $595.00

Catalog #: K1010003

Crystallization screen consisting of 48 unique crystallization reagents that were proven to be successful in crystallizing protein-DNA complexes. These 48 reagents were formulated after analyzing over 7000 published protein-DNA crystallization conditions and formulating unique reagents that included critical components for the growth of protein-DNA crystals such as the presence of polyamines, PEG of various molecular weights, divalent ions, various salts, reducing agents and other additives.

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Description

Crystallization Screen for Protein-DNA Complexes.

Product Data Sheet
Catalog # K1010003
Content 48 unique crystallization reagents (2 mL each)
Storage 2-8°C.
Keywords Crystallization screen, crystal screen, protein-DNA complex, protein-nucleic acids, crystal growth

 

References Related to Crystallization Screen for Protein-DNA Complexes

  • Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex. Scior A, Buntru A, Arnsburg K, Ast A, Iburg M, Juenemann K, Pigazzini ML, Mlody B, Puchkov D, Priller J, Wanker EE, Prigione A, Kirstein J. EMBO J. 2018 Jan 17;37(2):282-299.
  • Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC. Science. 2010 Sep 24;329(5999):1663-7.
  • DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins. Fontaine SN, Zheng D, Sabbagh JJ, Martin MD, Chaput D, Darling A, Trotter JH, Stothert AR, Nordhues BA, Lussier A, Baker J, Shelton L, Kahn M, Blair LJ, Stevens SM Jr, Dickey CA. EMBO J. 2016 Jul 15;35(14):1537-49.
  • The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development. Tebbenkamp ATN, Varela L, Choi J, Paredes MI, Giani AM, Song JE, Sestan-Pesa M, Franjic D, Sousa AMM, Liu ZW, Li M, Bichsel C, Koch M, Szigeti-Buck K, Liu F, Li Z, Kawasawa YI, Paspalas CD, Mineur YS, Prontera P, Merla G, Picciotto MR, Arnsten AFT, Horvath TL, Sestan N. Cell. 2018 Nov 1;175(4):1088-1104.e23.
  • Cellular DNAJA3, a Novel VP1-Interacting Protein, Inhibits Foot-and-Mouth Disease Virus Replication by Inducing Lysosomal Degradation of VP1 and Attenuating Its Antagonistic Role in the Beta Interferon Signaling Pathway. Zhang W, Yang F, Zhu Z, Yang Y, Wang Z, Cao W, Dang W, Li L, Mao R, Liu Y, Tian H, Zhang K, Liu X, Ma J, Zheng H. J Virol. 2019 Jun 14;93(13):e00588-19.
  • Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells. Vig S, Buitinga M, Rondas D, Crèvecoeur I, van Zandvoort M, Waelkens E, Eizirik DL, Gysemans C, Baatsen P, Mathieu C, Overbergh L. Cell Death Dis. 2019 Apr 5;10(4):309.