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A new interesting article has been published in Transfus Med. 2019 Dec; 29(6):442-447. doi: 10.1111/tme.12642. Epub 2019 Oct 17. and titled:

Non-conformities in tissue typing laboratory: Croatian experience.

Authors of this article are:

Katalinić N, Starčević A, Mavrinac M, Vuk T, Balen S.

A summary of the article is shown below:

OBJECTIVES: Our study aimed to determine the frequency and type of non-conformities that occurred in the tissue typing laboratory (TTL), Rijeka, Croatia, in order to evaluate the quality of testing and compliance with the requirements of the quality management system (QMS).BACKGROUND: The QMS in a TTL should lead to improvements in the accuracy and timeliness of results. One of its essential elements is non-conformity management.METHODS: A retrospective analysis of non-conformities recorded in the TTL Rijeka from 2006 to 2017 revealed the overall frequency of 0·43%. Classification was performed according to the examination phase, employee characteristics, relation to the field of work, part of laboratory and priority of testing.RESULTS: The most reported non-conformities occurred during the examination phase (54·0%), followed by the pre- and post-examination phase (31·2 and 14·8%, respectively). Inadequate competency and less experience were associated with the number of reported non-conformities while no difference was observed in relation to the profession or position in the laboratory. Non-conformities were equally distributed between organ transplantation and HLA-associated disease diagnostic processes, mostly referring to the entire laboratory work.CONCLUSION: Intensifying training and education, implementation of information technology into laboratory processes, more rigorous error detection and reporting are fundamental steps in improving quality of laboratory services.© 2019 British Blood Transfusion Society.

Check out the article’s website on Pubmed for more information:

This article is a good source of information and a good way to become familiar with topics such as: HLA; accreditation; histocompatibility testing; quality assurance; quality control.

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