Recombinant Human HGF Protein

Product Description

Recombinant Human HGF Protein
Catalog number: B2015562
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 μg
Molecular Weight or Concentration: 70 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: F TCF, Hepatocyte growth factor, Hepatopoeitin A, HGF, HGFB, HPTA, Scatter factor, SF
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Motoi S, Uesugi M, Obara T, Moriya K, Arita Y, Ogasawara H, Soejima M, Imai T, Kawano T. Serum APOA4 Pharmacodynamically Represents Administered Recombinant Human Hepatocyte Growth Factor (E3112) Int J Mol Sci. 2021 Apr 27;22(9):4578.
2: Mizuno S, Ikebuchi F, Fukuta K, Kato T, Matsumoto K, Adachi K, Abe T, Nakamura T. Recombinant human hepatocyte growth factor (HGF), but not rat HGF, elicits glomerular injury and albuminuria in normal rats via an immune complex-dependent mechanism Clin Exp Pharmacol Physiol. 2011 Mar;38(3):192-201.
3: Kim KH, Kim H. Progress of antibody-based inhibitors of the HGF-cMET axis in cancer therapy Exp Mol Med. 2017 Mar 24;49(3):e307.
4: Modica C, Basilico C, Chiriaco C, Borrelli N, Comoglio PM, Vigna E. A receptor-antibody hybrid hampering MET-driven metastatic spread J Exp Clin Cancer Res. 2021 Jan 14;40(1):32.
5: Yee CJ, DeFrances MC, Bell A, Bowen W, Petersen B, Michalopoulos GK, Zarnegar R. Expression and characterization of biologically active human hepatocyte growth factor (HGF) by insect cells infected with HGF-recombinant baculovirus Biochemistry. 1993 Aug 10;32(31):7922-31.
6: Reski R, Parsons J, Decker EL. Moss-made pharmaceuticals: from bench to bedside Plant Biotechnol J. 2015 Oct;13(8):1191-8.
7: Ido A, Numata M, Kodama M, Tsubouchi H. Mucosal repair and growth factors: recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease J Gastroenterol. 2005 Oct;40(10):925-31.
8: Ido A, Moriuchi A, Numata M, Murayama T, Teramukai S, Marusawa H, Yamaji N, Setoyama H, Kim ID, Chiba T, Higuchi S, Yokode M, Fukushima M, Shimizu A, Tsubouchi H. Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety J Transl Med. 2011 May 8;9:55.
9: Park JS, Kim H, Park J, Yu S, Kim D, Lee J, Oh H, Baek K, Yoon J. Overproduction of recombinant human hepatocyte growth factor in Chinese hamster ovary cells Protein Expr Purif. 2010 Apr;70(2):231-5.
10: Mizuta M, Hirano S, Kishimoto Y, Hiwatashi N, Tateya I, Kanemaru S, Nakamura T, Ito J. Pharmacokinetics and safety of human recombinant hepatocyte growth factor administered to vocal folds Laryngoscope. 2014 Sep;124(9):2131-5.

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