Beta-galactosidase Alpha-Complementation

Beta-galactosidase Alpha-Complementation is a biochemical phenomenon first documented by Agnes Ullmann, while working in the lab of Fran├žois Jacob and Jacques Monod. By means of molecular cloning, the native E. coli ╬▓-galactosidase enzyme can be split in two inactive fragments of different sizes. The smaller fragment, known as the alpha-peptide or enzyme donor, is about […]