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IgG Fc Fragment from Plasma (Native Human)

Original price was: $2,195.00.Current price is: $1,095.00.

Catalog Number: B2016903 (1 mg)
IgG Fc Fragment from Plasma (Native Human) is a high quality portion of the immunoglobulin G (IgG) antibody molecule that is found in the blood plasma of humans. The Fc fragment is the tail region of the IgG molecule that interacts with various immune cells and molecules to mediate immune responses, such as antibody-dependent cellular cytotoxicity and phagocytosis. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Product Description

IgG Fc Fragment from Plasma (Native Human)
Catalog number: B2016903
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 31 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: Immunoglubulin G Fc
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Anumula KR. Quantitative glycan profiling of normal human plasma derived immunoglobulin and its fragments Fab and Fc J Immunol Methods. 2012 Aug 31;382(1-2):167-76.
2: Müller HP, Rantamäki LK. Binding of native alpha 2-macroglobulin to human group G streptococci Infect Immun. 1995 Aug;63(8):2833-9.
3: Li R, Dowd V, Stewart DJ, Burton SJ, Lowe CR. Design, synthesis, and application of a protein A mimetic Nat Biotechnol. 1998 Feb;16(2):190-5.
4: Washburn N, Meccariello R, Duffner J, Getchell K, Holte K, Prod’homme T, Srinivasan K, Prenovitz R, Lansing J, Capila I, Kaundinya G, Manning AM, Bosques CJ. Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation Mol Cell Proteomics. 2019 Mar;18(3):534-545.
5: Feorino PM, Shore SL, Reimer CB. Detection by indirect immunofluorescence of Fc receptors in cells acutely infected with Herpes simplex virus Int Arch Allergy Appl Immunol. 1977;53(3):222-33.
6: Eckle I, Kolb G, Neurath F, Havemann K. Detection of granulocyte elastase specific IgG split products in rheumatoid synovial fluid Adv Exp Med Biol. 1988;240:531-4.
7: Stearns NA, Pisetsky DS. The role of monogamous bivalency and Fc interactions in the binding of anti-DNA antibodies to DNA antigen Clin Immunol. 2016 May;166-167:38-47.
8: Chu SY, Vostiar I, Karki S, Moore GL, Lazar GA, Pong E, Joyce PF, Szymkowski DE, Desjarlais JR. Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcgammaRIIb with Fc-engineered antibodies Mol Immunol. 2008 Sep;45(15):3926-33.
9: Kinet JP, Hunt J, Foidart JB, Desoroux A, Mahieu P. Ex vivo perfusion of plasma over protein A columns in human mammary adenocarcinoma. Evidence for a protein A leaking by radioimmunoassay Eur J Clin Invest. 1986 Feb;16(1):43-9.
10: Liang ZG, Kamada M, Koide SS. Properties of an immunoglobulin binding factor from human seminal plasma Biochem Int. 1991 Aug;24(6):1003-13.

Products Related to IgG Fc Fragment from Plasma (Native Human) can be found at Proteins

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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