Calcineurin Substrate (Highly Pure)

Product Description

Calcineurin Substrate (Highly Pure)
Catalog number: B2012993
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 ug
Molecular Weight or Concentration: 2192.3 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Calcineurin Substrate – Calbiochem, PP2B Substrate, RII Phosphopeptide, DLDVPIPGRFDRRVpSVAAE
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Creamer TP. Calcineurin Cell Commun Signal. 2020 Aug 28;18(1):137.
2: Medina DL, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, Montefusco S, Scotto-Rosato A, Prezioso C, Forrester A, Settembre C, Wang W, Gao Q, Xu H, Sandri M, Rizzuto R, De Matteis MA, Ballabio A. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB Nat Cell Biol. 2015 Mar;17(3):288-99.
3: Ulengin-Talkish I, Parson MAH, Jenkins ML, Roy J, Shih AZL, St-Denis N, Gulyas G, Balla T, Gingras AC, Várnai P, Conibear E, Burke JE, Cyert MS. Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane Nat Commun. 2021 Oct 18;12(1):6064.
4: Chen L, Song M, Yao C. Calcineurin in development and disease Genes Dis. 2021 Mar 15;9(4):915-927.
5: Klee CB, Draetta GF, Hubbard MJ. Calcineurin Adv Enzymol Relat Areas Mol Biol. 1988;61:149-200.
6: Hogan PG, Li H. Calcineurin Curr Biol. 2005 Jun 21;15(12):R442-3.
7: Chaklader M, Rothermel BA. Calcineurin in the heart: New horizons for an old friend Cell Signal. 2021 Nov;87:110134.
8: Liu Y, Xue X, Zhang H, Che X, Luo J, Wang P, Xu J, Xing Z, Yuan L, Liu Y, Fu X, Su D, Sun S, Zhang H, Wu C, Yang J. Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia Autophagy. 2019 Mar;15(3):493-509.
9: Williams RB, Johnson CN. A Review of Calcineurin Biophysics with Implications for Cardiac Physiology Int J Mol Sci. 2021 Oct 26;22(21):11565.
10: Li H, Hogan PG. Calcineurin: A star is reborn Cell Calcium. 2021 Mar;94:102324.

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