2-NBDG (Highly Pure)

Description

2-NBDG
Catalog number: MDP0879
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mg
Molecular Weight or Concentration: 342.26 g/mol
Supplied as: Powder
Applications: fluorescent tracer for monitoring glucose uptake in living cells
Storage: -20°C
Keywords: 2-[N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino]-2- Deoxy-D-Glucose
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
Indication for Use:This product is for Research Use Only. This product is NOT for human or animal use.

References:
1: Zou C, Wang Y, Shen Z. 2-NBDG as a fluorescent indicator for direct glucose
uptake measurement. J Biochem Biophys Methods. 2005 Sep 30;64(3):207-15.

2: Chen Y, Zhang J, Zhang XY. 2-NBDG as a marker for detecting glucose uptake in
reactive astrocytes exposed to oxygen-glucose deprivation in vitro. J Mol
Neurosci. 2015 Jan;55(1):126-130.

3: Ogawa T, Sasaki A, Ono K, Ohshika S, Ishibashi Y, Yamada K. Uptake of
fluorescent D- and L-glucose analogues, 2-NBDG and 2-NBDLG, into human
osteosarcoma U2OS cells in a phloretin-inhibitable manner. Hum Cell. 2021
Mar;34(2):634-643.

4: Cai H, Peng F. 2-NBDG fluorescence imaging of hypermetabolic circulating
tumor cells in mouse xenograft model of breast cancer. J Fluoresc. 2013
Jan;23(1):213-20.

5: Tao J, McCourt C, Sultana H, Nelson C, Driver J, Hackmann TJ. Use of a
Fluorescent Analog of Glucose (2-NBDG) To Identify Uncultured Rumen Bacteria
That Take Up Glucose. Appl Environ Microbiol. 2019 Mar 22;85(7):e03018-18.

6: Raeisi E, Mir LM. 2-NBDG, a fluorescent analogue of glucose, as a marker for
detecting cell electropermeabilization in vitro. J Membr Biol. 2012
Oct;245(10):633-42.

7: Yamamoto T, Tanaka S, Suga S, Watanabe S, Nagatomo K, Sasaki A, Nishiuchi Y,
Teshima T, Yamada K. Syntheses of 2-NBDG analogues for monitoring
stereoselective uptake of D-glucose. Bioorg Med Chem Lett. 2011 Jul
1;21(13):4088-96.

8: Jin J, Qiu S, Wang P, Liang X, Huang F, Wu H, Zhang B, Zhang W, Tian X, Xu R,
Shi H, Wu X. Cardamonin inhibits breast cancer growth by repressing
HIF-1α-dependent metabolic reprogramming. J Exp Clin Cancer Res. 2019 Aug
27;38(1):377.

9: Yamada K, Saito M, Matsuoka H, Inagaki N. A real-time method of imaging
glucose uptake in single, living mammalian cells. Nat Protoc. 2007;2(3):753-62.
10: Millon SR, Ostrander JH, Brown JQ, Raheja A, Seewaldt VL, Ramanujam N.
Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell
lines. Breast Cancer Res Treat. 2011 Feb;126(1):55-62.

Products Related to 2-NBDG: Carbohydrates