Human CDK2AP1 Protein

Product Description

Human CDK2AP1 Protein
Catalog number: B2011907
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 0.25 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: CDKA1 protein, CDK2AP 1, DOC 1R protein, CDK2AP1 protein, DOC 1 protein, CDK 2AP1 protein, CDK-2AP1 protein, CDK2AP 1 protein, DOC1R protein, CDKAP1 protein, CDK2AP1, Cyclin dependent kinase 2 associated protein 1 Deleted in oral cancer 1 protein, CDK2AP-
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Modzelewski AJ, Shao W, Chen J, Lee A, Qi X, Noon M, Tjokro K, Sales G, Biton A, Anand A, Speed TP, Xuan Z, Wang T, Risso D, He L. A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development Cell. 2021 Oct 28;184(22):5541-5558.e22.
2: Alsayegh KN, Sheridan SD, Iyer S, Rao RR. Knockdown of CDK2AP1 in human embryonic stem cells reduces the threshold of differentiation PLoS One. 2018 May 7;13(5):e0196817.
3: Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, Maglaqui M, Lee HW, Prestegard JH, Montelione GT. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region J Biol Chem. 2012 May 11;287(20):16541-9.
4: Alsayegh KN, Gadepalli VS, Iyer S, Rao RR. Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence PLoS One. 2015 Mar 18;10(3):e0120782.
5: Gera R, Mokbel L, Jiang WG, Mokbel K. mRNA Expression of CDK2AP1 in Human Breast Cancer: Correlation with Clinical and Pathological Parameters Cancer Genomics Proteomics. 2018 Nov-Dec;15(6):447-452.
6: Xu Y, Wang J, Fu S, Wang Z. Knockdown of CDK2AP1 by RNA interference inhibits cell growth and tumorigenesis of human glioma Neurol Res. 2014 Jul;36(7):659-65.
7: Wong DT, Kim JJ, Khalid O, Sun HH, Kim Y. Double edge: CDK2AP1 in cell-cycle regulation and epigenetic regulation J Dent Res. 2012 Mar;91(3):235-41.
8: Buajeeb W, Zhang X, Ohyama H, Han D, Surarit R, Kim Y, Wong DT. Interaction of the CDK2-associated protein-1, p12(DOC-1/CDK2AP1), with its homolog, p14(DOC-1R) Biochem Biophys Res Commun. 2004 Mar 19;315(4):998-1003.
9: Sun M, Jiang R, Wang G, Zhang C, Li J, Jin C, Zhang X. Cyclin-dependent kinase 2-associated protein 1 suppresses growth and tumorigenesis of lung cancer Int J Oncol. 2013 Apr;42(4):1376-82.
10: Wu LC, Chen YL, Wu WR, Li CF, Huang HY, Lee SW, Chang SL, Lin CY, Chen YH, Hsu HP, Lu PJ, Shiue YL. Expression of cyclin-dependent kinase 2-associated protein 1 confers an independent prognosticator in nasopharyngeal carcinoma: a cohort study J Clin Pathol. 2012 Sep;65(9):795-801.

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