X-Neu5Ac (X-Sialic acid, X-NANA)

$199.00

Catalog number: MDP0878
Name: 5-Bromo-4-chloroindol-3-yl-5-acetamido-3,5-dideoxy-_-D-glycero-D-dalacto-2-nonulopyranosidonic acid
Other name(s): X-Neu5Ac (X-Sialic acid, X-NANA)
Molecular Formula: C19H22N2O9BrCl
Molecular Mass: 537.74
CAS #: 265979-52-0
Storage Temperature: -20 C
Amount needed (x 1 mg):

In stock

SKU: MDP0878 Category:

Description

X-Neu5Ac (X-Sialic acid, X-NANA)

Price per 1 mg: $199
Catalog number: MDP0878
Name: 5-Bromo-4-chloroindol-3-yl-5-acetamido-3,5-dideoxy-_-D-glycero-D-dalacto-2-nonulopyranosidonic acid
Other name(s): X-Neu5Ac (X-Sialic acid, X-NANA)
Molecular Formula: C19H22N2O9BrCl
Molecular Mass: 537.74
CAS #: 265979-52-0
Storage Temperature: -20 C
Ships from: California
Structure:


Additional information:

Indication for Use:
This product if for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use.

Safety:
User must review the Material Safety Data Sheet (MSDS) provided with this product. In addition, this product should not be ingested, inhaled, swallowed or put in contact with eyes, skin or clothes.

References

1: Fujii I, Iwabuchi Y, Teshima T, Shiba T, Kikuchi M. X-Neu5Ac: a novel
substrate for chromogenic assay of neuraminidase activity in bacterial
expression systems. Bioorg Med Chem. 1993 Aug;1(2):147-9.

2: Saito M, Hagita H, Iwabuchi Y, Fujii I, Ikeda K, Ito M. Fluorescent
cytochemical detection of sialidase activity using 5-bromo-4-chloroindol-3-yl-
alpha- D- N-acetylneuraminic acid as the substrate. Histochem Cell Biol. 2002
May;117(5):453-8.

3: Kogan TP, Revelle BM, Tapp S, Scott D, Beck PJ. A single amino acid residue
can determine the ligand specificity of E-selectin. J Biol Chem. 1995 Jun
9;270(23):14047-55.

4: Berg EL, Magnani J, Warnock RA, Robinson MK, Butcher EC. Comparison of
L-selectin and E-selectin ligand specificities: the L-selectin can bind the
E-selectin ligands sialyl Le(x) and sialyl Le(a). Biochem Biophys Res Commun.
1992 Apr 30;184(2):1048-55.

5: Suzuki Y, Toda Y, Tamatani T, Watanabe T, Suzuki T, Nakao T, Murase K, Kiso
M, Hasegawa A, Tadano-Aritomi K, et al. Sulfated glycolipids are ligands for a
lymphocyte homing receptor, L-selectin (LECAM-1), Binding epitope in sulfated
sugar chain. Biochem Biophys Res Commun. 1993 Jan 29;190(2):426-34.

6: Saito M, Hagita H, Ito M, Ando S, Yu RK. Age-dependent reduction in sialidase
activity of nuclear membranes from mouse brain. Exp Gerontol. 2002
Jul;37(7):937-41.

7: Horie K, Sakagami M, Kuramochi K, Hanasaki K, Hamana H, Ito T. Enhanced
accumulation of sialyl Lewis X-carboxymethylpullulan conjugate in acute
inflammatory lesion. Pharm Res. 1999 Feb;16(2):314-20.

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