Cystatin C (Native Human)

Product Description

Cystatin C (Native Human)
Catalog number: B2016877
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 ug
Molecular Weight or Concentration: 13 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Cystatin-3, CST3, Gamma Trace, Neuroendocrine basic polypepide
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Li C, Ma Y, Yang C, Hua R, Xie W, Zhang L. Association of Cystatin C Kidney Function Measures With Long-term Deficit-Accumulation Frailty Trajectories and Physical Function Decline JAMA Netw Open. 2022 Sep 1;5(9):e2234208.
2: Dahl H, Meyer K, Sandnes K, Welland NL, Arnesen I, Marti HP, Dierkes J, Lysne V. Cystatin C proteoforms in chronic kidney disease PLoS One. 2023 Feb 1;18(2):e0269436.
3: Abrahamson M, Dalbøge H, Olafsson I, Carlsen S, Grubb A. Efficient production of native, biologically active human cystatin C by Escherichia coli FEBS Lett. 1988 Aug 15;236(1):14-8.
4: Zahran A, El-Husseini A, Shoker A. Can cystatin C replace creatinine to estimate glomerular filtration rate? A literature review Am J Nephrol. 2007;27(2):197-205.
5: Zhou Y, Zhou Y, Li J, Chen J, Yao Y, Yu L, Peng D, Wang M, Su D, He Y, Gou L. Efficient expression, purification and characterization of native human cystatin C in Escherichia coli periplasm Protein Expr Purif. 2015 Jul;111:18-22.
6: Abrahamson M, Mason RW, Hansson H, Buttle DJ, Grubb A, Ohlsson K. Human cystatin C. role of the N-terminal segment in the inhibition of human cysteine proteinases and in its inactivation by leucocyte elastase Biochem J. 1991 Feb 1;273 ( Pt 3)(Pt 3):621-6.
7: Perlenfein TJ, Murphy RM. Expression, purification, and characterization of human cystatin C monomers and oligomers Protein Expr Purif. 2016 Jan;117:35-43.
8: Mindikoglu AL, Pappas SC. New Developments in Hepatorenal Syndrome Clin Gastroenterol Hepatol. 2018 Feb;16(2):162-177.e1.
9: Barrett AJ, Davies ME, Grubb A. The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors Biochem Biophys Res Commun. 1984 Apr 30;120(2):631-6.
10: Prądzińska M, Behrendt I, Astorga-Wells J, Manoilov A, Zubarev RA, Kołodziejczyk AS, Rodziewicz-Motowidło S, Czaplewska P. Application of amide hydrogen/deuterium exchange mass spectrometry for epitope mapping in human cystatin C Amino Acids. 2016 Dec;48(12):2809-2820.

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