Ribonuclease H (RNase H)

Product Description

Ribonuclease H (RNase H)
Catalog number: B2016638
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 units
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: rnase h
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chan SH, Whipple JM, Dai N, Kelley TM, Withers K, Tzertzinis G, Corrêa IR Jr, Robb GB. RNase H-based analysis of synthetic mRNA 5′ cap incorporation RNA. 2022 Aug;28(8):1144-1155.
2: Kanaya S. Ribonuclease H FEBS J. 2009 Mar;276(6):1481.
3: Hyjek M, Figiel M, Nowotny M. RNases H: Structure and mechanism DNA Repair (Amst). 2019 Dec;84:102672.
4: Beverly M, Dell A, Parmar P, Houghton L. Label-free analysis of mRNA capping efficiency using RNase H probes and LC-MS Anal Bioanal Chem. 2016 Jul;408(18):5021-30.
5: Ilina TV, Brosenitsch T, Sluis-Cremer N, Ishima R. Retroviral RNase H: Structure, mechanism, and inhibition Enzymes. 2021;50:227-247.
6: Cerritelli SM, Crouch RJ. Ribonuclease H: the enzymes in eukaryotes FEBS J. 2009 Mar;276(6):1494-505.
7: Moelling K. Targeting the retroviral ribonuclease H by rational drug design AIDS. 2012 Oct 23;26(16):1983-93.
8: Heuzé J, Kemiha S, Barthe A, Vilarrubias AT, Aouadi E, Aiello U, Libri D, Lin YL, Lengronne A, Poli J, Pasero P. RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart EMBO J. 2023 Dec 1;42(23):e113104.
9: Schultz SJ, Champoux JJ. RNase H activity: structure, specificity, and function in reverse transcription Virus Res. 2008 Jun;134(1-2):86-103.
10: Wang Y , Hu N , Liu C , Nie C , He M , Zhang J , Yu Q , Zhao C , Chen T , Chu X . An RNase H-powered DNA walking machine for sensitive detection of RNase H and the screening of related inhibitors Nanoscale. 2020 Jan 23;12(3):1673-1679.

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