Retinol Binding Protein (Native Lyophilized)

Product Description

Retinol Binding Protein (Native Lyophilized)
Catalog number: B2010386
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 21 kDa
Supplied as: Lyophilized powder
Appearance: White powder
Applications: native RBP protein with mutiple functions that include binding retinol (a compound with key roles in the regulation of gene expression). Serum concentrations of RBP can be used to monitor liver function, malnutrition, Cystic Fibrosis and renal function.
Storage: 2-8C
Keywords: RBP, Human RBP, hRBP
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Perduca M, Nicolis S, Mannucci B, Galliano M, Monaco HL. Human plasma
retinol-binding protein (RBP4) is also a fatty acid-binding protein. Biochim
Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):458-466.

2: Est CB, Murphy RM. Retinol binding protein IV purified from Escherichia coli
using intein-mediated cleavage as a suitable replacement for serum sources.
Protein Expr Purif. 2020 Mar;167:105542.

3: Barletta GP, Franchini G, Corsico B, Fernandez-Alberti S. Fatty Acid and
Retinol-Binding Protein: Unusual Protein Conformational and Cavity Changes
Dictated by Ligand Fluctuations. J Chem Inf Model. 2019 Aug 26;59(8):3545-3555.

4: Zanotti G, Berni R. Plasma retinol-binding protein: structure and
interactions with retinol, retinoids, and transthyretin. Vitam Horm.
2004;69:271-95.

5: Monaco HL. The transthyretin-retinol-binding protein complex. Biochim Biophys
Acta. 2000 Oct 18;1482(1-2):65-72.

6: Rask L, Anundi H, Böhme J, Eriksson U, Fredriksson A, Nilsson SF, Ronne H,
Vahlquist A, Peterson PA. The retinol-binding protein. Scand J Clin Lab Invest
Suppl. 1980;154:45-61.

7: Raghu P, Sivakumar B. Interactions amongst plasma retinol-binding protein,
transthyretin and their ligands: implications in vitamin A homeostasis and
transthyretin amyloidosis. Biochim Biophys Acta. 2004 Dec 1;1703(1):1-9.
8: Gaetani S, Bellovino D, Apreda M, Devirgiliis C. Hepatic synthesis,
maturation and complex formation between retinol-binding protein and
transthyretin. Clin Chem Lab Med. 2002 Dec;40(12):1211-20.

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