Platelet-derived Growth Factor-BB (Human)

Product Description

Platelet-derived Growth Factor-BB (Human, Recombinant)
Catalog number: B2010323
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Platelet-derived Growth Factor-BB (Human, Recombinant) expressed in P. pastoris. This protein acts as the most active PDGF isoform which binds to PDGF receptor and promotes diverse cell types proliferation and osteogenesis.
Storage: -20C
Keywords: rHuPDGF-BB; PDGF-2; GDGF; ODGF; SIS; SSV
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Scheines C, Hokett SD, Katancik JA. Recombinant Human Platelet-Derived Growth
Factor-BB in Human Alveolar Ridge Augmentation: A Review of the Literature. Int
J Oral Maxillofac Implants. 2018 Sep/Oct;33(5):1047-1056.

2: Daniels TR, Anderson J, Swords MP, Maislin G, Donahue R, Pinsker E, Quiton
JD. Recombinant Human Platelet-Derived Growth Factor BB in Combination With a
Beta-Tricalcium Phosphate (rhPDGF-BB/β-TCP)-Collagen Matrix as an Alternative to
Autograft. Foot Ankle Int. 2019 Sep;40(9):1068-1078.

3: Sun H, Lu PP, Zhou PH, Sun SW, Zhang HT, Liu YJ, Yang X, Shen XF, Yang HL.
Recombinant human platelet-derived growth factor-BB versus autologous bone graft
in foot and ankle fusion: A systematic review and meta-analysis. Foot Ankle
Surg. 2017 Mar;23(1):32-39.

4: Joshi AA, Padhye AM, Gupta HS. Platelet derived growth factor-BB levels in
gingival crevicular fluid of localized intrabony defect sites treated with
platelet rich fibrin membrane or collagen membrane containing recombinant human
platelet derived growth factor-BB: A randomized clinical and biochemical study.
J Periodontol. 2019 Jul;90(7):701-708.

5: Younger A, Penner M, Montijo HE. Vancouver Experience of Recombinant Human
Platelet-Derived Growth Factor. Foot Ankle Clin. 2016 Dec;21(4):771-776.

6: Dodd A, Daniels TR. Injectable Recombinant Human Platelet-derived Growth
Factor in Collagen Carrier for Hindfoot Fusion. Foot Ankle Clin. 2016
Dec;21(4):777-791.

7: Chen W, Wang F, Tian C, Wang Y, Xu S, Wang R, Hou K, Zhao P, Yu L, Lu Z, Xia
Q. Transgenic Silkworm-Based Silk Gland Bioreactor for Large Scale Production of
Bioactive Human Platelet-Derived Growth Factor (PDGF-BB) in Silk Cocoons. Int J
Mol Sci. 2018 Aug 27;19(9):2533.

8: Friedlaender GE, Lin S, Solchaga LA, Snel LB, Lynch SE. The role of
recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic
bone repair and regeneration. Curr Pharm Des. 2013;19(19):3384-90.

9: Babavalian H, Latifi AM, Shokrgozar MA, Bonakdar S, Tebyanian H, Shakeri F.
Cloning and expression of recombinant human platelet-derived growth factor-BB in
Pichia Pink. Cell Mol Biol (Noisy-le-grand). 2016 Jul 31;62(8):45-51.

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