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Interleukin-3 (Human, Recombinant)

Original price was: $695.00.Current price is: $495.00.

Catalog Number: B2010310 (10 ug)
Interleukin-3 (Human, Recombinant) is a high quality research product used as highly pure Interleukin-3 (Human, Recombinant) expressed in CHO. This protein acts as a hematopoietic cytokine with effects on platelet and neutrophil counts as well as putative applications in patients with secondary hematopoietic failure. Custom bulk orders of this product are available upon request.

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Product Description

Interleukin-3 (Human, Recombinant)
Catalog number: B2010310
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Interleukin-3 (Human, Recombinant) expressed in CHO. This protein acts as a hematopoietic cytokine with effects on platelet and neutrophil counts as well as putative applications in patients with secondary hematopoietic failure.
Storage: -20C
Keywords: rHuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wagemaker G, Burger H, van Gils FC, van Leen RW, Wielenga JJ. Interleukin 3.
Biotherapy. 1990;2(4):337-45.

2: Bessler H, Bergman M, Salman H. Interleukin-3 and stress. Biomed
Pharmacother. 2000 Jul;54(6):299-304.

3: Bridges AG, Helm TN, Bergfeld WF, Lawlor KB, Dijkstra J.
Interleukin 3-induced urticaria-like eruption. J Am Acad Dermatol. 1996
Jun;34(6):1076-8.

4: Lindemann A, Mertelsmann R. Interleukin 3 and its receptor. Cancer Treat Res.
1995;80:107-42.

5: Yen JJ, Yang-Yen HF. Transcription factors mediating interleukin-3 survival
signals. Vitam Horm. 2006;74:147-63.

6: Aldinucci D, Olivo K, Lorenzon D, Poletto D, Gloghini A, Carbone A, Pinto A.
The role of interleukin-3 in classical Hodgkin’s disease. Leuk Lymphoma. 2005
Mar;46(3):303-11.

7: Frendl G. Interleukin 3: from colony-stimulating factor to pluripotent
immunoregulatory cytokine. Int J Immunopharmacol. 1992 Apr;14(3):421-30.

8: Yang YC, Clark SC. Human interleukin 3: analysis of the gene and its role in
the regulation of hematopoiesis. Int J Cell Cloning. 1990 Jan;8 Suppl 1:121-8;
discussion 128-9.

9: Monette FC. The role of interleukin 3 and heme in the induction of
erythropoiesis. Ann N Y Acad Sci. 1989;554:49-58.

10: Yao S, Young IG, Norton RS, Murphy JM. Murine interleukin-3: structure,
dynamics, and conformational heterogeneity in solution. Biochemistry. 2011 Apr
5;50(13):2464-77.
11: Carr PD, Ewens CL, Dai J, Ollis DL, Murphy JM, Jackson CJ, Young IG. Crystal
structure of the mouse interleukin-3 β-receptor: insights into interleukin-3
binding and receptor activation. Biochem J. 2014 Nov 1;463(3):393-403.

Products Related to Interleukin-3 (Human, Recombinant) : Proteins

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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