Indian Hedgehog Protein (Human Recombinant)

Product Description

Indian hedgehog protein
Catalog number: B2010367
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Indian hedgehog protein expressed in E. coli. This protein acts as protein is involved in chondrocyte differentiation, proliferation and maturation especially during endochondral ossification.
Storage: -20C
Keywords: rHuIHH; HHG-2
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Deng A, Zhang H, Hu M, Liu S, Gao Q, Wang Y, Guo C. Knockdown of Indian
hedgehog protein induces an inhibition of cell growth and differentiation in
osteoblast MC3T3‑E1 cells. Mol Med Rep. 2017 Dec;16(6):7987-7992.

2: Plubell DL, Fenton AM, Rosario S, Bergstrom P, Wilmarth PA, Clark WM, Zakai
NA, Quinn JF, Minnier J, Alkayed NJ, Fazio S, Pamir N. High-Density Lipoprotein
Carries Markers That Track With Recovery From Stroke. Circ Res. 2020 Oct
23;127(10):1274-1287.

3: Smith K, Alnifaidy R, Wei Q, Nieman LK. Endometrial Indian hedgehog
expression is decreased in women with endometriosis. Fertil Steril. 2011 Jun
30;95(8):2738-41.e1-3.

4: Sieker JT, Kunz M, Weißenberger M, Gilbert F, Frey S, Rudert M, Steinert AF.
Direct bone morphogenetic protein 2 and Indian hedgehog gene transfer for
articular cartilage repair using bone marrow coagulates. Osteoarthritis
Cartilage. 2015 Mar;23(3):433-42.

5: Kim SY, Im GI. The expressions of the SOX trio, PTHrP (parathyroid hormone-
related peptide)/IHH (Indian hedgehog protein) in surgically induced
osteoarthritis of the rat. Cell Biol Int. 2011 May;35(5):529-35.

6: Parra S, Heras M, Herrero P, Amigó N, Garcés E, Girona J, Correig X, Canela
N, Castro A. Gelsolin: a new biomarker of disease activity in SLE patients
associated with HDL-c. Rheumatology (Oxford). 2020 Mar 1;59(3):650-661.

7: Yang L, Gee AO, Zielinska-Kwiatkowska A, Chansky HA. Generation and
characterization of mice with mesenchyme-specific deletion of the entire ESET
histone methyltransferase protein. Genesis. 2018 Feb;56(2).

8: Hussain MZ, Talapaneni AK, Prasad M, Krishnan R. Serum PTHrP level as a
biomarker in assessing skeletal maturation during circumpubertal development. Am
J Orthod Dentofacial Orthop. 2013 Apr;143(4):515-21.
9: Kim HK, Feng GS, Chen D, King PD, Kamiya N. Targeted disruption of Shp2 in
chondrocytes leads to metachondromatosis with multiple cartilaginous
protrusions. J Bone Miner Res. 2014 Mar;29(3):761-9.

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