Human Transforming Growth Factor β1

Product Description

Human Transforming Growth Factor β1
Catalog number: B2010333
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Transforming Growth Factor β1 expressed in CHO. This protein acts as a multifunctional cytokine which participates in foetal development, control of cell growth and differentiation.
Storage: -20C
Keywords: TGF-beta-1; TGFB1; TGFB; rHuTGF-β1
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Lichtman MK, Otero-Vinas M, Falanga V. Transforming growth factor beta
(TGF-β) isoforms in wound healing and fibrosis. Wound Repair Regen. 2016
Mar;24(2):215-22.

2: Lodyga M, Hinz B. TGF-β1 – A truly transforming growth factor in fibrosis and
immunity. Semin Cell Dev Biol. 2020 May;101:123-139.

3: Kim KK, Sheppard D, Chapman HA. TGF-β1 Signaling and Tissue Fibrosis. Cold
Spring Harb Perspect Biol. 2018 Apr 2;10(4):a022293.

4: Kudva AK, Dikina AD, Luyten FP, Alsberg E, Patterson J. Gelatin microspheres
releasing transforming growth factor drive in vitro chondrogenesis of human
periosteum derived cells in micromass culture. Acta Biomater. 2019
May;90:287-299.

5: Hinz B. The extracellular matrix and transforming growth factor-β1: Tale of a
strained relationship. Matrix Biol. 2015 Sep;47:54-65.

6: Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA. Latent TGF-β
structure and activation. Nature. 2011 Jun 15;474(7351):343-9.

7: Tarbit E, Singh I, Peart JN, Rose’Meyer RB. Biomarkers for the identification
of cardiac fibroblast and myofibroblast cells. Heart Fail Rev. 2019
Jan;24(1):1-15.

8: Wattanapakkavong K, Srisuwan T. Release of Transforming Growth Factor Beta 1
from Human Tooth Dentin after Application of Either ProRoot MTA or Biodentine as
a Coronal Barrier. J Endod. 2019 Jun;45(6):701-705.
9: Delaney K, Kasprzycka P, Ciemerych MA, Zimowska M. The role of TGF-β1 during
skeletal muscle regeneration. Cell Biol Int. 2017 Jul;41(7):706-715.

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