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Human Epidermal Growth Factor Receptor

$695.00 $495.00

Catalog Number: B2010377 (10 ug)
Human Epidermal Growth Factor Receptor is a high quality research product used as highly pure Human Epidermal Growth Factor Receptor expressed in Sf9 insect cells. This protein acts as a member of the tyrosine kinase receptors family and plays important roles in cell growth and differentiation. Custom bulk orders of this product are available upon request.

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SKU: B2010377 Categories: , ,

Description

Human Epidermal Growth Factor Receptor
Catalog number: B2010377
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Epidermal Growth Factor Receptor expressed in Sf9 insect cells. This protein acts as a member of the tyrosine kinase receptors family and plays important roles in cell growth and differentiation.
Storage: -20C
Keywords: rHuEGFR, His; ErbB1; HER1; ERBB
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Rajaram P, Chandra P, Ticku S, Pallavi BK, Rudresh KB, Mansabdar P. Epidermal
growth factor receptor: Role in human cancer. Indian J Dent Res. 2017 Nov-
Dec;28(6):687-694.

2: Liu X, Wang P, Zhang C, Ma Z. Epidermal growth factor receptor (EGFR): A
rising star in the era of precision medicine of lung cancer. Oncotarget. 2017
Jul 25;8(30):50209-50220.

3: Sabbah DA, Hajjo R, Sweidan K. Review on Epidermal Growth Factor Receptor
(EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR
Inhibitors. Curr Top Med Chem. 2020;20(10):815-834.

4: Kobayashi Y, Mitsudomi T. Not all epidermal growth factor receptor mutations
in lung cancer are created equal: Perspectives for individualized treatment
strategy. Cancer Sci. 2016 Sep;107(9):1179-86.

5: Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J. A structural perspective on
the regulation of the epidermal growth factor receptor. Annu Rev Biochem.
2015;84:739-64.

6: Gan HK, Cvrljevic AN, Johns TG. The epidermal growth factor receptor variant
III (EGFRvIII): where wild things are altered. FEBS J. 2013 Nov;280(21):5350-70.

7: Schneider MR, Wolf E. The epidermal growth factor receptor ligands at a
glance. J Cell Physiol. 2009 Mar;218(3):460-6.

8: Voldborg BR, Damstrup L, Spang-Thomsen M, Poulsen HS. Epidermal growth factor
receptor (EGFR) and EGFR mutations, function and possible role in clinical
trials. Ann Oncol. 1997 Dec;8(12):1197-206.
9: Tomas A, Futter CE, Eden ER. EGF receptor trafficking: consequences for
signaling and cancer. Trends Cell Biol. 2014 Jan;24(1):26-34. doi:
10.1016/j.tcb.2013.11.002. Epub 2013 Nov 29. PMID: 24295852; PMCID: PMC3884125.

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