Human Epidermal Growth Factor Receptor
Original price was: $695.00.$495.00Current price is: $495.00.
Catalog Number: B2010377 (10 ug)
Human Epidermal Growth Factor Receptor is a high quality research product used as highly pure Human Epidermal Growth Factor Receptor expressed in Sf9 insect cells. This protein acts as a member of the tyrosine kinase receptors family and plays important roles in cell growth and differentiation. Custom bulk orders of this product are available upon request.
In stock
Product Description
Human Epidermal Growth Factor Receptor
Catalog number: B2010377
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Epidermal Growth Factor Receptor expressed in Sf9 insect cells. This protein acts as a member of the tyrosine kinase receptors family and plays important roles in cell growth and differentiation.
Storage: -20C
Keywords: rHuEGFR, His; ErbB1; HER1; ERBB
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Rajaram P, Chandra P, Ticku S, Pallavi BK, Rudresh KB, Mansabdar P. Epidermal
growth factor receptor: Role in human cancer. Indian J Dent Res. 2017 Nov-
Dec;28(6):687-694.
2: Liu X, Wang P, Zhang C, Ma Z. Epidermal growth factor receptor (EGFR): A
rising star in the era of precision medicine of lung cancer. Oncotarget. 2017
Jul 25;8(30):50209-50220.
3: Sabbah DA, Hajjo R, Sweidan K. Review on Epidermal Growth Factor Receptor
(EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR
Inhibitors. Curr Top Med Chem. 2020;20(10):815-834.
4: Kobayashi Y, Mitsudomi T. Not all epidermal growth factor receptor mutations
in lung cancer are created equal: Perspectives for individualized treatment
strategy. Cancer Sci. 2016 Sep;107(9):1179-86.
5: Kovacs E, Zorn JA, Huang Y, Barros T, Kuriyan J. A structural perspective on
the regulation of the epidermal growth factor receptor. Annu Rev Biochem.
2015;84:739-64.
6: Gan HK, Cvrljevic AN, Johns TG. The epidermal growth factor receptor variant
III (EGFRvIII): where wild things are altered. FEBS J. 2013 Nov;280(21):5350-70.
7: Schneider MR, Wolf E. The epidermal growth factor receptor ligands at a
glance. J Cell Physiol. 2009 Mar;218(3):460-6.
8: Voldborg BR, Damstrup L, Spang-Thomsen M, Poulsen HS. Epidermal growth factor
receptor (EGFR) and EGFR mutations, function and possible role in clinical
trials. Ann Oncol. 1997 Dec;8(12):1197-206.
9: Tomas A, Futter CE, Eden ER. EGF receptor trafficking: consequences for
signaling and cancer. Trends Cell Biol. 2014 Jan;24(1):26-34. doi:
10.1016/j.tcb.2013.11.002. Epub 2013 Nov 29. PMID: 24295852; PMCID: PMC3884125.
Products Related to Human Epidermal Growth Factor Receptor : Proteins
Additional Information
Weight | 48 oz |
---|---|
Dimensions | 8 × 8 × 8 in |
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