Human DKK-1 Protein

Product Description

Human DKK-1 Protein
Catalog number: B2014695
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 μg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Dickkopf related protein 1, DKK1, DKK, SK
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Jang J, Jung Y, Kim Y, Jho EH, Yoon Y. LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974 Sci Rep. 2017 Jan 27;7:41612.
2: Shou J, Ali-Osman F, Multani AS, Pathak S, Fedi P, Srivenugopal KS. Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA Oncogene. 2002 Jan 31;21(6):878-89.
3: Fedi P, Bafico A, Nieto Soria A, Burgess WH, Miki T, Bottaro DP, Kraus MH, Aaronson SA. Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling J Biol Chem. 1999 Jul 2;274(27):19465-72.
4: Oh H, Chun CH, Chun JS. Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice Arthritis Rheum. 2012 Aug;64(8):2568-78.
5: Xu J, Sadahira T, Kinoshita R, Li SA, Huang P, Wada K, Araki M, Ochiai K, Noguchi H, Sakaguchi M, Nasu Y, Watanabe M. Exogenous DKK-3/REIC inhibits Wnt/β-catenin signaling and cell proliferation in human kidney cancer KPK1 Oncol Lett. 2017 Nov;14(5):5638-5642.
6: Suda T, Yamashita T, Sunagozaka H, Okada H, Nio K, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S. Dickkopf-1 Promotes Angiogenesis and is a Biomarker for Hepatic Stem Cell-like Hepatocellular Carcinoma Int J Mol Sci. 2022 Mar 3;23(5):2801.
7: Li Y, Fu H, Wang H, Luo S, Wang L, Chen J, Lu H. GLP-1 promotes osteogenic differentiation of human ADSCs via the Wnt/GSK-3β/β-catenin pathway Mol Cell Endocrinol. 2020 Sep 15;515:110921.
8: Kataoka K, Sakaguchi M, Li KP, Taketa C, Yamamoto K, Du G, Funahashi H, Murata H, Huh NH. Internalization of REIC/Dkk-3 protein by induced pluripotent stem cell-derived embryoid bodies and extra-embryonic tissues Int J Mol Med. 2010 Dec;26(6):853-9.
9: Zhou Y, Li W, Xu Q, Huang Y. Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU J Exp Clin Cancer Res. 2010 Oct 4;29(1):131.
10: Malaei F, Rasaee MJ, Paknejad M, Latifi AM, Rahbarizadeh F. Production and Characterization of Monoclonal and Polyclonal Antibodies Against Truncated Recombinant Dickkopf-1 as a Candidate Biomarker Monoclon Antib Immunodiagn Immunother. 2018 Dec;37(6):257-264.

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