Anti-Sialyl 6,6′-disulfo LacNAc Antibody

Product Description

Anti-Sialyl 6,6′-disulfo LacNAc Antibody
Catalog number: B2015010
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: N/A
Supplied as: Liquid
Applications: molecular tool for various biochemical applications
Storage: -20° C
Keywords: Anti-Sialyl 6,6′-disulfo LacNAc Monoclonal Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Xiong W, Liu W, Nishida S, Komiyama D, Liu W, Hirakawa J, Kawashima H. Therapeutic Effects of an Anti-sialyl Lewis X Antibody in a Murine Model of Allergic Asthma Int J Mol Sci. 2021 Sep 15;22(18):9961.
2: Liu W, Xiong W, Liu W, Wei Z, Abo H, Kawashima H. Therapeutic Effects of an Anti-Sialyl Lewis x Antibody in a Murine Model of Acute Lung Injury Monoclon Antib Immunodiagn Immunother. 2023 Jun;42(3):97-103.
3: Ohmori K, Takada A, Ohwaki I, Takahashi N, Furukawa Y, Maeda M, Kiso M, Hasegawa A, Kannagi M, Kannagi R. A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cells Blood. 1993 Nov 1;82(9):2797-805.
4: Kumamoto K, Mitsuoka C, Izawa M, Kimura N, Otsubo N, Ishida H, Kiso M, Yamada T, Hirohashi S, Kannagi R. Specific detection of sialyl Lewis X determinant carried on the mucin GlcNAcbeta1–>6GalNAcalpha core structure as a tumor-associated antigen Biochem Biophys Res Commun. 1998 Jun 18;247(2):514-7.
5: Tsuboi K, Asao T, Ide M, Hashimoto S, Noguchi K, Kominato Y, Saniabadi AR, Kuwano H, Yazawa S. Alpha1,2fucosylation is a superior predictor of postoperative prognosis for colorectal cancer compared with blood group A, B, or sialyl Lewis X antigen generated within colorectal tumor tissues Ann Surg Oncol. 2007 Jun;14(6):1880-9.
6: Markiv A, Anani B, Durvasula RV, Kang AS. Module based antibody engineering: a novel synthetic REDantibody J Immunol Methods. 2011 Feb 1;364(1-2):40-9.
7: Ohmori K, Fukui F, Kiso M, Imai T, Yoshie O, Hasegawa H, Matsushima K, Kannagi R. Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells Blood. 2006 Apr 15;107(8):3197-204.
8: Sawada M, Takada A, Ohwaki I, Takahashi N, Tateno H, Sakamoto J, Kannagi R. Specific expression of a complex sialyl Lewis X antigen on high endothelial venules of human lymph nodes: possible candidate for L-selectin ligand Biochem Biophys Res Commun. 1993 May 28;193(1):337-47.
9: Mitoma J, Miyazaki T, Sutton-Smith M, Suzuki M, Saito H, Yeh JC, Kawano T, Hindsgaul O, Seeberger PH, Panico M, Haslam SM, Morris HR, Cummings RD, Dell A, Fukuda M. The N-glycolyl form of mouse sialyl Lewis X is recognized by selectins but not by HECA-452 and FH6 antibodies that were raised against human cells Glycoconj J. 2009 Jul;26(5):511-23.
10: Zhu Y, Groth T, Kelkar A, Zhou Y, Neelamegham S. A GlycoGene CRISPR-Cas9 lentiviral library to study lectin binding and human glycan biosynthesis pathways Glycobiology. 2021 Apr 1;31(3):173-180.

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