AFP Antibody Monoclonal (Mouse)

From: $495.00

Catalog #: A2010013-7E9, A2010013-3F6, A2010013-Pair

Alpha-Fetoprotein (AFP) is a protein essentially produced during the fetal stages of human development. As such, it is abundant in fetal serum and scarce in adult serum. Because of its ability to binds metals such as copper and nickel as well as metabolites such as fatty acids and bilirubin, AFP is believed to be a fetal version of the serum albumins found in adults. Levels of AFP in the serum of pregnant women can be correlated to the health of the fetus. The provided monoclonal antibody (7E9) specifically recognizes human AFP and can be used in immunoassays and immuno-detection. A second clone (3F6) is available and can be paired with with clone 7E9. Bulk pricing and biotinylation services are available.

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Description

AFP Antibody Monoclonal

Product Data Sheet
Catalog # A2010013
Size 1.0 mg
Other Names AFP antibody, a-Fetoprotein antibody, alpha-fetoprotein antibody
Host Mouse Monoclonal (Clone 7E9 and 3F6)
Concentration 3 mg/mL
Purity Affinity purified of protein A (> 95%)
Storage 2-8°C (short term). -20°C (long term). Avoid repeated freeze-thaw.
Supplied as Liquid solution
Buffer PBS1x, pH 7.4 + 0.05% sodium azide
Keywords AFP, a-Fetoprotein

References

  • Carlsson, R. (1981). Alpha-Fetoprotein: aspects on function and synthesis. Lund.
  • Spear, B. (2001). Alpha (α)-Fetoprotein. Encyclopedia of Genetics, 42.
  • Kaplan, D. E. (2011). Alpha-Fetoprotein Diagnostics. Encyclopedia of Cancer, 146–147.
  • Kithier, K. (2011). Alpha-Fetoprotein. Encyclopedia of Cancer, 143–146.
  • Yeaney, N. K. (2004). Alpha-Fetoprotein Screening. Encyclopedia of Women’s Health, 85–87.
  • Post-treatment alpha-fetoprotein response predicts prognosis of patients with hepatocellular carcinoma: A meta-analysis.
    He C, Peng W, Liu X, Li C, Li X, Wen TF. Medicine (Baltimore). 2019 Aug;98(31):e16557.
  • Alpha-fetoprotein in pericardial, peritoneal, and pleural fluids: A body fluid matrix evaluation.
    Owen WE, Hunsaker JJH, Genzen JR. Clin Biochem. 2018 Jun;56:109-112.
  • The alpha-fetoprotein third domain receptor binding fragment: in search of scavenger and associated receptor targets.
    Mizejewski GJ. J Drug Target. 2015;23(6):538-51.
  • A novel ECL sensor based on a boronate affinity molecular imprinting technique and functionalized SiO(2)@CQDs/AuNPs/MPBA nanocomposites for sensitive determination of alpha-fetoprotein.
    Mo G, He X, Zhou C, Ya D, Feng J, Yu C, Deng B. Biosens Bioelectron. 2019 Feb 1;126:558-564.
  • The use of a monoclonal antibody against alpha-fetoprotein for the radioimmunodetection of hepatocellular carcinoma.
    Springolo E, Kew MC, Esser J, Beyers M, Conradie JD, Levin J. Hepatology. 1989 Jan;9(1):116-20.
  • Gold nanoparticle labeling with tyramide signal amplification for highly sensitive detection of alpha fetoprotein in human serum by ICP-MS.
    Li X, Chen B, He M, Xiao G, Hu B. Talanta. 2018 Jan 1;176:40-46.
  • Alpha-fetoprotein in the woodchuck model of hepadnavirus infection and disease: immunochemical analysis of woodchuck alpha-fetoprotein and measurement in serum by quantitative monoclonal radioimmunoassay.
    Cote PJ, Pohl C, Boyd J, Tennant BC, Gerin JL. Hepatology. 1990 May;11(5):824-33.