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SARS-CoV-2 Spike S1 Domain (High Purity)

$895.00

Catalog Number: B2010507 (100 ug)
SARS-CoV-2 Spike S1 Domain is a highly pure recombinant SARS-CoV-2 S1 domain from the origical wild type lineage expressed in insect cells. This product has been used as molecular component of many serological and antigenic assays for SARS-CoV-2. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010507 Categories: ,

Description

SARS-CoV-2 Spike S1 Domain
Catalog number: B2010507
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 76 kDa
Supplied as: Lyophilized Powder
Applications: molecular component of many serological and antigenic assays for SARS-CoV-2
Storage: -20℃
Keywords: Spike S1, S1 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Weisblum Y, Schmidt F, Zhang F, DaSilva J, Poston D, Lorenzi JC, Muecksch F,
Rutkowska M, Hoffmann HH, Michailidis E, Gaebler C, Agudelo M, Cho A, Wang Z,
Gazumyan A, Cipolla M, Luchsinger L, Hillyer CD, Caskey M, Robbiani DF, Rice CM,
Nussenzweig MC, Hatziioannou T, Bieniasz PD. Escape from neutralizing antibodies
by SARS-CoV-2 spike protein variants. Elife. 2020 Oct 28;9:e61312.

2: Walls AC, Park YJ, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure,
Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell. 2020 Apr
16;181(2):281-292.e6.

3: Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin
AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr,
Bjorkman PJ. SARS-CoV-2 neutralizing antibody structures inform therapeutic
strategies. Nature. 2020 Dec;588(7839):682-687.

4: Wang Q, Zhang Y, Wu L, Niu S, Song C, Zhang Z, Lu G, Qiao C, Hu Y, Yuen KY,
Wang Q, Zhou H, Yan J, Qi J. Structural and Functional Basis of SARS-CoV-2 Entry
by Using Human ACE2. Cell. 2020 May 14;181(4):894-904.e9.

5: Ou X, Liu Y, Lei X, Li P, Mi D, Ren L, Guo L, Guo R, Chen T, Hu J, Xiang Z,
Mu Z, Chen X, Chen J, Hu K, Jin Q, Wang J, Qian Z. Characterization of spike
glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with
SARS-CoV. Nat Commun. 2020 Mar 27;11(1):1620.

6: Xia X. Domains and Functions of Spike Protein in Sars-Cov-2 in the Context of
Vaccine Design. Viruses. 2021 Jan 14;13(1):109.

7: Barnes CO, West AP Jr, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR,
Koranda N, Gristick HB, Gaebler C, Muecksch F, Lorenzi JCC, Finkin S, Hägglöf T,
Hurley A, Millard KG, Weisblum Y, Schmidt F, Hatziioannou T, Bieniasz PD, Caskey
M, Robbiani DF, Nussenzweig MC, Bjorkman PJ. Structures of Human Antibodies
Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of
Antibodies. Cell. 2020 Aug 20;182(4):828-842.e16.

8: Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Antón-Plágaro C,
Shoemark DK, Simón-Gracia L, Bauer M, Hollandi R, Greber UF, Horvath P, Sessions
RB, Helenius A, Hiscox JA, Teesalu T, Matthews DA, Davidson AD, Collins BM,
Cullen PJ, Yamauchi Y. Neuropilin-1 is a host factor for SARS-CoV-2 infection.
Science. 2020 Nov 13;370(6518):861-865.

9: Wu Y, Li C, Xia S, Tian X, Kong Y, Wang Z, Gu C, Zhang R, Tu C, Xie Y, Yang
Z, Lu L, Jiang S, Ying T. Identification of Human Single-Domain Antibodies
against SARS-CoV-2. Cell Host Microbe. 2020 Jun 10;27(6):891-898.e5.
10: Buzhdygan TP, DeOre BJ, Baldwin-Leclair A, Bullock TA, McGary HM, Khan JA,
Razmpour R, Hale JF, Galie PA, Potula R, Andrews AM, Ramirez SH. The SARS-CoV-2
spike protein alters barrier function in 2D static and 3D microfluidic in-vitro
models of the human blood-brain barrier. Neurobiol Dis. 2020 Dec;146:105131.

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