Methylmalonic Acid BSA Conjugate

Product Description

Methylmalonic Acid BSA Conjugate
Catalog number: B2010260
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 1.0 mg
pH: 7.4
Supplied as: Ready-to-use
Appearance: Solution
Applications: highly pure conjugate of BSA to methylmalonic Acid, a dicarboxylic acid, C-methylated derivative of malonate.
Storage: -20C
Keywords: methylmalonate BSA conjugate
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through0.22 um.

References:
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Prospective Study on Serum Methylmalonic Acid and Homocysteine in Pregnant
Women. Nutrients. 2016 Dec 8;8(12):797.

2: Fu X, Francisco C, Pattengale P, O’Gorman MR, Mitchell WG. An Adolescent with
Increased Plasma Methylmalonic Acid and Total Homocysteine. Clin Chem. 2017
Jun;63(6):1069-1072.

3: Lindberg M, Borgstrøm Hager H, Brokner M. Week-to-week biological variation
of methylmalonic acid and homocysteine in healthy women. Scand J Clin Lab
Invest. 2019 Jul;79(4):247-250.

4: Kushnir MM, Nelson GJ, Frank EL, Rockwood AL. High-Throughput Analysis of
Methylmalonic Acid in Serum, Plasma, and Urine by LC-MS/MS. Method for Analyzing
Isomers Without Chromatographic Separation. Methods Mol Biol. 2016;1378:159-73.

6: Fighera MR, Queiroz CM, Stracke MP, Brauer MC, González-Rodríguez LL, Frussa-
Filho R, Wajner M, de Mello CF. Ascorbic acid and alpha-tocopherol attenuate
methylmalonic acid-induced convulsions. Neuroreport. 1999 Jul 13;10(10):2039-43.

7: Kölker S, Schwab M, Hörster F, Sauer S, Hinz A, Wolf NI, Mayatepek E,
Hoffmann GF, Smeitink JA, Okun JG. Methylmalonic acid, a biochemical hallmark of
methylmalonic acidurias but no inhibitor of mitochondrial respiratory chain. J
Biol Chem. 2003 Nov 28;278(48):47388-93.

8: Schroder TH, Mattman A, Sinclair G, Vallance HD, Lamers Y. Reference interval
of methylmalonic acid concentrations in dried blood spots of healthy, term
newborns to facilitate neonatal screening of vitamin B12 deficiency. Clin
Biochem. 2016 Sep;49(13-14):973-8.

9: Hultberg B, Jensen E, Dehlin O, Hagberg B, Samuelsson G, Svensson T.
Concentrations of plasma methylmalonic acid in 80-year-olds show only weak
relation to psychological performance. Clin Chem Lab Med. 1999 Oct;37(10):963-7.

10: Klee GG. Cobalamin and folate evaluation: measurement of methylmalonic acid
and homocysteine vs vitamin B(12) and folate. Clin Chem. 2000 Aug;46(8 Pt
2):1277-83.

11: Andrade VM, Dal Pont HS, Leffa DD, Damiani AP, Scaini G, Hainzenreder G,
Streck EL, Ferreira GC, Schuck PF. Methylmalonic acid administration induces DNA
damage in rat brain and kidney. Mol Cell Biochem. 2014 Jun;391(1-2):137-45.

12: Lindgren A. Elevated serum methylmalonic acid. How much comes from cobalamin
deficiency and how much comes from the kidneys? Scand J Clin Lab Invest.
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