L-Pyroglutamyl-L-alanine

Description

L-Pyroglutamyl-L-alanine
Catalog number: MDP0113
CAS Number: 128802-78-8
Sequence: L-Pyroglutamyl-L-alanine
Amount: 200 mg
Molecular Weight: 200 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Chepkova AN, Doreulee NV, Trofimov SS, Gudasheva TA, Ostrovskaya RU, Skrebitsky VG. Nootropic compound L-pyroglutamyl-D-alanine-amide restores hippocampal long-term potentiation impaired by exposure to ethanol in rats Neurosci Lett. 1995 Mar 31;188(3):163-6.
2: Ramasubbu N, Parthasarathy R. Crystal structure and conformation of L-pyroglutamyl-L-alanine Int J Pept Protein Res. 1989 May;33(5):328-34.
3: Ostrovskaia RU, Trofimov SS, Gudasheva TA, Smol’nikova NM, Nemova EP, Krapivin SV, Savchenko NM, Tsirenina ML, Ushakov AN, Mel’nik EI, et al. [L-pyroglutamyl-D-alanine amide normalizes the function of the developing brain damaged by antenatal alcoholization in rats] Biull Eksp Biol Med. 1990 Dec;110(12):613-6.
4: Vysotskii AL, Vysotskii DL, Gudasheva TA, Ostrovskaya RU, Anokhin KV. Modulation of long-term memory by delayed administration of the amide of L-pyroglutamyl-D-alanine, a nootropic agent, in spaced and massed training in rats Neurosci Behav Physiol. 1999 Mar-Apr;29(2):137-42.
5: Trofimov SS, Ostrovskaia RU, Smol’nikova NM, Nemova EP, Gudasheva TA, Kuznetsova EA, Voronina TA. [The correction with nooglutil and L-pyroglutamyl-D-alanine amide of cognitive disorders in rats due to intrauterine hypoxia] Eksp Klin Farmakol. 1995 Nov-Dec;58(6):10-3.
6: Ostrovskaia RU, Gudasheva TA, Trofimov SS, Romanova GA, Dobrynin VP. [Behavioral and electrophysiologic characteristics of a peptide analog of piracetam–L-pyroglutamyl-D-alanine amide] Biull Eksp Biol Med. 1987 Nov;104(11):576-9.
7: Tsuru D, Fujiwara K, Kado K. Purification and characterization of L-pyrrolidonecarboxylate peptidase from Bacillus amyloiliquefaciens J Biochem. 1978 Aug;84(2):467-76.
8: Caldwell KA. In vitro digestion of gliadin by gastrointestinal enzymes and by pyrrolidonecarboxylate peptidase Am J Clin Nutr. 1980 Feb;33(2):293-302.
9: Vysotskiĭ AL, Vysotskiĭ DL, Gudasheva TA, Ostrovskaia RU, Anokhin KV. [Modulation of the long-term memory by delayed administration of the nootropic agent L-pyroglutamyl-D-alaninamide during spaced and massed training of rats] Ross Fiziol Zh Im I M Sechenova. 1998 Mar;84(3):157-63.
10: Yoneda M, Sato Y, Nakamura K, Yokohama S, Kono T, Watanobe H, Terano A. Involvement of calcitonin gene-related peptide and capsaicin-sensitive afferents in central thyrotropin-releasing hormone-induced hepatic cytoprotection Eur J Pharmacol. 2003 Oct 8;478(2-3):173-7.

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