Intrinsic Factor from Porcine Gastric Mucosa


Catalog Number: B2010532 (0.1 mg)
Intrinsic Factor from porcine gastric mucosa is a highly pure natural binder and transportor of Vitamin B12. This product has been used as versatile molecular tool in Vitamin B12 assay development. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Intrinsic Factor from porcine gastric mucosa
Catalog number: B2010532
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: na
Supplied as: Solution
Applications: versatile molecular tool in Vitamin B12 assay development
Storage: -20C
Keywords: IF
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Khan S, Del-Duca C, Fenton E, Holding S, Hirst J, Doré PC, Sewell WA. Limited
value of testing for intrinsic factor antibodies with negative gastric parietal
cell antibodies in pernicious anaemia. J Clin Pathol. 2009 May;62(5):439-41.

2: Hippe E, Schwartz M. Intrinsic factor activity of stomach preparations from
various animal species. Scand J Haematol. 1971;8(4):276-81.

3: Marcoullis G, Merivuori H, Gräsbeck R. Comparative studies on intrinsic
factor and cobalophilin in different parts of the gastrointestinal tract of the
pig. Biochem J. 1978 Sep 1;173(3):705-12.

4: Marcoullis G, Gräsbeck R, Salonen EM. Identification and characterization of
intrinsic factor and cobalophilin from pig ileal and pyloric mucosa. Biochim
Biophys Acta. 1977 May 26;497(3):663-72.

5: Gordon MM, Howard T, Becich MJ, Alpers DH. Cathepsin L mediates intracellular
ileal digestion of gastric intrinsic factor. Am J Physiol. 1995 Jan;268(1 Pt

6: Francis GL, Smith GW, Toskes PP, Sanders EG. Purification of hog gastric
intrinsic factor by a simple two-step procedure based on affinity chromatography
and a selective guanidine hydrochloride gradient. Gastroenterology. 1977

7: Allen RH, Mehlman CS. Isolation of gastric vitamin B 12 -binding proteins
using affinity chromatography. II. Purification and properties of hog intrinsic
factor and hog nonintrinsic factor. J Biol Chem. 1973 May 25;248(10):3670-80.

8: Lobie PE, García-Aragón J, Waters MJ. Growth hormone (GH) regulation of
gastric structure and function in the GH-deficient rat: up-regulation of
intrinsic_factor. Endocrinology. 1992 May;130(5):3015-24.

9: Safi A, Saunier M, Gastin I, Alibada Y, Dugue B, Gueant JL. Intrinsic_factor
covalently bound to Sepharose as affinity medium for the purification of a
soluble intrinsic factor receptor from human urine. J Chromatogr B Biomed Appl.
1995 Feb 3;664(1):253-9.
10: Kouvonen I, Gräsbeck R. The role of sialic acid in the binding of calcium
ions to intrinsic factor and its intestinal receptor. Biochim Biophys Acta. 1984
Feb 14;797(2):163-70.

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