Human Lck Protein Activated

Product Description

Human Lck Protein Activated
Catalog number: B2014429
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 μg
Molecular Weight or Concentration: 59 kDa
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Lck Protein, activated, 10 µg
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Lyu M, Yi X, Huang Z, Chen Y, Ai Z, Liang Y, Feng Q, Xiang Z. A transcriptomic analysis based on aberrant methylation levels revealed potential novel therapeutic targets for nasopharyngeal carcinoma Ann Transl Med. 2022 Jan;10(2):47.
3: Levite M. Dopamine and T cells: dopamine receptors and potent effects on T cells, dopamine production in T cells, and abnormalities in the dopaminergic system in T cells in autoimmune, neurological and psychiatric diseases Acta Physiol (Oxf). 2016 Jan;216(1):42-89.
4: Wu L, Brzostek J, Sakthi Vale PD, Wei Q, Koh CKT, Ong JXH, Wu LZ, Tan JC, Chua YL, Yap J, Song Y, Tan VJY, Tan TYY, Lai J, MacAry PA, Gascoigne NRJ. CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance Cell Rep Med. 2023 Feb 21;4(2):100917.
5: Ciarimboli G, Struwe K, Arndt P, Gorboulev V, Koepsell H, Schlatter E, Hirsch JR. Regulation of the human organic cation transporter hOCT1 J Cell Physiol. 2004 Dec;201(3):420-8.
6: Gary JM, Simmons JK, Xu J, Zhang S, Peat TJ, Watson N, Gamache BJ, Zhang K, Kovalchuk AL, Michalowski AM, Chen JQ, Thaiwong T, Kiupel M, Gaikwad S, Etienne M, Simpson RM, Dubois W, Testa JR, Mock BA. Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis Mol Cancer Ther. 2020 Oct;19(10):2221-2232.
7: Brner C, Smida M, Hllt V, Schraven B, Kraus J. Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling J Biol Chem. 2009 Dec 18;284(51):35450-60.
8: Jury EC, Isenberg DA, Mauri C, Ehrenstein MR. Atorvastatin restores Lck expression and lipid raft-associated signaling in T cells from patients with systemic lupus erythematosus J Immunol. 2006 Nov 15;177(10):7416-22.
9: Salinthone S, Yadav V, Schillace RV, Bourdette DN, Carr DW. Lipoic acid attenuates inflammation via cAMP and protein kinase A signaling PLoS One. 2010 Sep 28;5(9):e13058.
10: Ilangumaran S, Briol A, Hoessli DC. CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes Blood. 1998 May 15;91(10):3901-8.

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