Human CHMP5 Protein

Product Description

Human CHMP5 Protein
Catalog number: B2011944
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 27 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Vps60 protein, HSPC177 protein, CHMP 5, C9orf83 protein, CHMP-5 protein, Charged multivesicular body protein 5 protein, CHMP 5 protein, CHMP5, PNAS-2 protein, CGI-34 protein, SNF7DC2 protein, CHMP-5
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Son F, Umphred-Wilson K, Shim JH, Adoro S. Assessment of ESCRT Protein CHMP5 Activity on Client Protein Ubiquitination by Immunoprecipitation and Western Blotting Methods Mol Biol. 2019;1998:219-226.
2: Skalicky JJ, Arii J, Wenzel DM, Stubblefield WM, Katsuyama A, Uter NT, Bajorek M, Myszka DG, Sundquist WI. Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport J Biol Chem. 2012 Dec 21;287(52):43910-26.
3: Wi SM, Min Y, Lee KY. Charged MVB protein 5 is involved in T-cell receptor signaling Exp Mol Med. 2016 Jan 29;48(1):e206.
4: Wu SH, Chang MH, Chen YH, Wu HL, Chua HH, Chien CS, Ni YH, Chen HL, Chen HL. The ESCRT-III molecules regulate the apical targeting of bile salt export pump J Biomed Sci. 2021 Mar 9;28(1):19.
5: Vild CJ, Li Y, Guo EZ, Liu Y, Xu Z. A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5 J Biol Chem. 2015 Mar 13;290(11):7291-303.
6: Dai E, Meng L, Kang R, Wang X, Tang D. ESCRT-III-dependent membrane repair blocks ferroptosis Biochem Biophys Res Commun. 2020 Feb 5;522(2):415-421.
7: Mo JS, Han SH, Yun KJ, Chae SC. MicroRNA 429 regulates the expression of CHMP5 in the inflammatory colitis and colorectal cancer cells Inflamm Res. 2018 Dec;67(11-12):985-996.
8: Wang H, Liu J, Wang F, Chen M, Xiao Z, Ouyang R, Fei A, Shen Y, Pan S. The role of charged multivesicular body protein 5 in programmed cell death in leukemic cells Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):383-90.
9: Greenblatt MB, Park KH, Oh H, Kim JM, Shin DY, Lee JM, Lee JW, Singh A, Lee KY, Hu D, Xiao C, Charles JF, Penninger JM, Lotinun S, Baron R, Ghosh S, Shim JH. CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts J Exp Med. 2015 Jul 27;212(8):1283-301.
10: Wang HR, Xiao ZY, Chen M, Wang FL, Liu J, Zhong H, Zhong JH, Ou-Yang RR, Shen YL, Pan SM. Anti-CHMP5 single chain variable fragment antibody retrovirus infection induces programmed cell death of AML leukemic cells in vitro Acta Pharmacol Sin. 2012 Jun;33(6):809-16.

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