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Carnitine Acetyltransferase

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2016563 (1 mL)
Carnitine Acetyltransferase is a high quality enzyme that plays a key role in fatty acid metabolism. It is responsible for transferring an acetyl group from carnitine to coenzyme A, which is necessary for the breakdown of fatty acids for energy production. This enzyme is primarily found in the mitochondria of cells and is important for maintaining energy balance in the cell. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Carnitine Acetyltransferase
Catalog number: B2016563
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: N/A
Supplied as: Suspension
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: acetylcarnitine transferase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Song MJ, Park CH, Kim H, Han S, Lee SH, Lee DH, Chung JH. Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction-induced cellular senescence in dermal fibroblasts Aging Cell. 2023 Nov;22(11):e14000.
2: Ramsay RR, Naismith JH. A snapshot of carnitine acetyltransferase Trends Biochem Sci. 2003 Jul;28(7):343-6.
3: Hong JH, Lee MK. Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway Diabetes Metab J. 2021 Nov;45(6):933-947.
4: Mao H, Angelini A, Li S, Wang G, Li L, Patterson C, Pi X, Xie L. CRAT links cholesterol metabolism to innate immune responses in the heart Nat Metab. 2023 Aug;5(8):1382-1394.
5: Bremer J. Carnitine–metabolism and functions Physiol Rev. 1983 Oct;63(4):1420-80.
6: Scholte HR, Rodrigues Pereira R, de Jonge PC, Luyt-Houwen IE, Hedwig M, Verduin M, Ross JD. Primary carnitine deficiency J Clin Chem Clin Biochem. 1990 May;28(5):351-7.
7: Berg SM, Beck-Nielsen H, Færgeman NJ, Gaster M. Carnitine acetyltransferase: A new player in skeletal muscle insulin resistance? Biochem Biophys Rep. 2016 Nov 18;9:47-50.
8: Seiler SE, Koves TR, Gooding JR, Wong KE, Stevens RD, Ilkayeva OR, Wittmann AH, DeBalsi KL, Davies MN, Lindeboom L, Schrauwen P, Schrauwen-Hinderling VB, Muoio DM. Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise Cell Metab. 2015 Jul 7;22(1):65-76.
9: Lasheras-Otero I, Feliu I, Maillo A, Moreno H, Redondo-Muñoz M, Aldaz P, Bocanegra A, Olias-Arjona A, Lecanda F, Fernandez-Irigoyen J, Santamaria E, Larrayoz IM, Gomez-Cabrero D, Wellbrock C, Vicent S, Arozarena I. The Regulators of Peroxisomal Acyl-Carnitine Shuttle CROT and CRAT Promote Metastasis in Melanoma J Invest Dermatol. 2023 Feb;143(2):305-316.e5.
10: Kalaria RN, Harik SI. Carnitine acetyltransferase activity in the human brain and its microvessels is decreased in Alzheimer’s disease Ann Neurol. 1992 Oct;32(4):583-6.

Products Related to Carnitine Acetyltransferase can be found at Enzymes

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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