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ALC-0315 Lipid (Highly Pure for Nanolipids)

$495.00

Catalog Number: B2010473 (5 mg)
ALC-0315 Lipid (Highly Pure) is a highly pure ALC-0315 lipid for a wide variety of chemical and biochemical applications. ALC-0315 has been recently used in the formulation of lipid nanoparticles used in mRNA vaccines. This product is for research use only and is not for human or animal use. Custom bulk orders of this product are available upon request.
Live Enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010473 Categories: , ,

Description

ALC-0315 Lipid (Highly Pure)
Catalog number: B2010473
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: na
Supplied as: Neat
Appearance: Neat
Applications: highly pure ALC-0315 lipid for a wide variety of chemical and biochemical applications. ALC-0315 has been recently used in the formulation of lipid nanoparticles used in mRNA vaccines. This product is for research use only and is not for human or animal use.
Storage: -20°C
Keywords: [(4-hydroxybutyl)azanediyl]di(hexane-6,1-diyl) bis(2-hexyldecanoate)
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Takalkar D, Desai N. Nanolipid Gel of an Antimycotic Drug for Treating
Vulvovaginal Candidiasis-Development and Evaluation. AAPS PharmSciTech. 2018
Apr;19(3):1297-1307.

2: Selvaraj BR, Sridhar SK, Kesavan BR, Palagati S. Application of Statistical
Tooling Techniques for Designing of Carvedilol Nanolipid Transferosomes and its
Dermatopharmacokinetic and Pharmacodynamic Studies. Pharm Nanotechnol.
2020;8(6):452-470.

3: Vohra T, Kaur I, Heer H, Murthy RR. Nanolipid carrier-based thermoreversible
gel for localized delivery of docetaxel to breast cancer. Cancer Nanotechnol.
2013;4(1-3):1-12.

4: Sharma N, Bhandari S, Deshmukh R, Yadav AK, Mishra N. Development and
characterization of embelin-loaded nanolipid carriers for brain targeting. Artif
Cells Nanomed Biotechnol. 2017 May;45(3):409-413.

5: Gharat SA, Momin M, Bhavsar C. Oral Squamous Cell Carcinoma: Current
Treatment Strategies and Nanotechnology-Based Approaches for Prevention and
Therapy. Crit Rev Ther Drug Carrier Syst. 2016;33(4):363-400.

6: Patil A, Lakhani P, Taskar P, Avula B, Majumdar S. Carboxyvinyl Polymer and
Guar-Borate Gelling System Containing Natamycin Loaded PEGylated Nanolipid
Carriers Exhibit Improved Ocular Pharmacokinetic Parameters. J Ocul Pharmacol
Ther. 2020 Jul/Aug;36(6):410-420.

7: Jojo GM, Kuppusamy G, De A, Karri VVSNR. Formulation and optimization of
intranasal nanolipid carriers of pioglitazone for the repurposing in Alzheimer’s
disease using Box-Behnken design. Drug Dev Ind Pharm. 2019 Jul;45(7):1061-1072.

8: Morrison ED, Guo M, Maia J, Nelson D, Swaminathan S, Kandimalla KK, Lee H,
Zasadzinski J, McCormick A, Marti J, Garhofer B. Dense nanolipid fluid
dispersions comprising ibuprofen: Single step extrusion process and drug
properties. Int J Pharm. 2021 Apr 1;598:120289.

9: Keck CM, Schwabe K. Silver-nanolipid complex for application to atopic
dermatitis skin: rheological characterization, in vivo efficiency and theory of
action. J Biomed Nanotechnol. 2009 Aug;5(4):428-36.

10: Mishra N, Sharma S, Deshmukh R, Kumar A, Sharma R. Development and
Characterization of Nasal Delivery of Selegiline Hydrochloride Loaded Nanolipid
Carriers for the Management of Parkinson’s Disease. Cent Nerv Syst Agents Med
Chem. 2019;19(1):46-56.
11: Krishnan Y, Mukundan S, Akhil S, Gupta S, Viswanad V. Enhanced Lymphatic
Uptake of Leflunomide Loaded Nanolipid Carrier via Chylomicron Formation for the
Treatment of Rheumatoid Arthritis. Adv Pharm Bull. 2018 Jun;8(2):257-265.

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