β-Defensin-4 (Human)

Product Description

β-Defensin-4 (Human)
Catalog number: MDP0770
CAS Number: N/A
Sequence: Glu-Leu-Asp-Arg-Ile-Cys-Gly-Tyr-Gly-Thr-Ala-Arg-Cys-Arg-Lys-Lys-Cys-Arg-Ser-Gln-Glu-Tyr-Arg-Ile-Gly-Arg-Cys-Pro-Asn-Thr-Tyr-Ala-Cys-Cys-Leu-Arg-Lys (Disulfide bonds between Cys6-Cys33, Cys13-Cys27, and Cys17-Cys34)
Amount: 100 ug
Molecular Weight: 4366 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Cieślik M, Bagińska N, Górski A, Jończyk-Matysiak E. Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response Cells. 2021 Nov 3;10(11):2991.
2: Schröder JM, Harder J. Human beta-defensin-2 Int J Biochem Cell Biol. 1999 Jun;31(6):645-51.
3: Prahl A, Pazgier M, Alexandratos J, Lubkowski J. Human β-defensin 4 – defensin without the “twist” Postepy Biochem. 2016;62(3):349-361.
4: Bindra GK, Williams SA, Lay FT, Baxter AA, Poon IKH, Hulett MD, Phan TK. Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration Biomolecules. 2022 Feb 6;12(2):264.
5: Mariscalco MM. Human beta 2 defensin-is it about prediction or is it about the science? A tale of innate immunity* Pediatr Crit Care Med. 2013 Oct;14(8):824-6.
6: Sharma H, Nagaraj R. Human β-defensin 4 with non-native disulfide bridges exhibit antimicrobial activity PLoS One. 2015 Mar 18;10(3):e0119525.
7: Noronha SA, Noronha SM, Lanziani LE, Ipolito MZ, Ferreira LM, Gragnani A. Human beta defensin-4 and keratinocyte growth factor gene expression in cultured keratinocyte and fibroblasts of burned patients Acta Cir Bras. 2014;29 Suppl 3:39-43.
8: Musumeci G, Carnazza ML, Leonardi R, Loreto C. Expression of β-defensin-4 in “an in vivo and ex vivo model” of human osteoarthritic knee meniscus Knee Surg Sports Traumatol Arthrosc. 2012 Feb;20(2):216-22.
9: Smiley AK, Gardner J, Klingenberg JM, Neely AN, Supp DM. Expression of human beta defensin 4 in genetically modified keratinocytes enhances antimicrobial activity J Burn Care Res. 2007 Jan-Feb;28(1):127-32.
10: Kotani H, Koshizuka T, Matsubara K, Nishiyama K, Sugiyama T, Suzutani T. Relationship Between Human β-Defensin 2 and the Vaginal Environment Jpn J Infect Dis. 2020 May 22;73(3):214-220.

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