Native Bovine ECGF Extract with Heparin

Product Description

Native Bovine ECGF Extract with Heparin
Catalog number: B2016483
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 mg
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Fibroblast growth factor 1, Endothelial Cell Growth Factor, Heparin-binding growth factor 1, HBGF-1, Acidic fibroblast growth factor, aFGF
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Maciag T, Mehlman T, Friesel R, Schreiber AB. Heparin binds endothelial cell growth factor, the principal endothelial cell mitogen in bovine brain Science. 1984 Aug 31;225(4665):932-5.
2: Greisler HP, Klosak JJ, Dennis JW, Karesh SM, Ellinger J, Kim DU. Biomaterial pretreatment with ECGF to augment endothelial cell proliferation J Vasc Surg. 1987 Feb;5(2):393-9.
3: Del Vecchio PJ, Bizios R, Holleran LA, Judge TK, Pinto GL. Inhibition of human scleral fibroblast proliferation with heparin Invest Ophthalmol Vis Sci. 1988 Aug;29(8):1272-6.
4: Burgess WH, Mehlman T, Friesel R, Johnson WV, Maciag T. Multiple forms of endothelial cell growth factor. Rapid isolation and biological and chemical characterization J Biol Chem. 1985 Sep 25;260(21):11389-92.
5: Schreiber AB, Kenney J, Kowalski J, Thomas KA, Gimenez-Gallego G, Rios-Candelore M, Di Salvo J, Barritault D, Courty J, Courtois Y, Moenner M, Loret C, Burgess WH, Mehlman T, Friesel R, Johnson W, Maciag T. A unique family of endothelial cell polypeptide mitogens: the antigenic and receptor cross-reactivity of bovine endothelial cell growth factor, brain-derived acidic fibroblast growth factor, and eye-derived growth factor-II J Cell Biol. 1985 Oct;101(4):1623-6.
6: Jaye M, Burgess WH, Shaw AB, Drohan WN. Biological equivalence of natural bovine and recombinant human alpha-endothelial cell growth factors J Biol Chem. 1987 Dec 5;262(34):16612-7.
7: Leslie CC, McCormick-Shannon K, Mason RJ. Heparin-binding growth factors stimulate DNA synthesis in rat alveolar type II cells Am J Respir Cell Mol Biol. 1990 Jan;2(1):99-106.
8: Libermann TA, Friesel R, Jaye M, Lyall RM, Westermark B, Drohan W, Schmidt A, Maciag T, Schlessinger J. An angiogenic growth factor is expressed in human glioma cells EMBO J. 1987 Jun;6(6):1627-32.
9: Hahn B, Knorr M, Wunderlich K, Dartsch PC. [Growth characteristics of bovine retinal pericytes in culture] Ophthalmologe. 1994 Jun;91(3):368-72.
10: Allikmets EYu, Danilov SM. Mitogen-induced disorganization of capillary-like structures formed by human large vessel endothelial cells in vitro Tissue Cell. 1986;18(4):481-9.

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