MES (Biotechnology Grade – 100g)


Catalog #: B2010026 (100 g)

MES is on Good′s list of the most extensively used biological buffers. MES does not complex most metals used in biology and has a useful buffering range of 5.5-6.7.

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SKU: B2010026 Categories: ,


MES (Biotechnology Grade – 100g)

Catalog number: B2010026
Lot number: Batch Dependent
Expiration date: Batch Dependent
Weight: 100 g
Formula C6H13NO4S
MW 195.24
Other names 2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid
Application: Buffer and solution formulation, reagent formulation
Shelf-Life Two years from date of manufacture
Storage: Room temperature
Keywords: mes powder, mes buffer, mes buffer solution
Grade Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
References 1: Fitzgerald PM, Wu JK, Toney JH. Unanticipated inhibition of the metallo-beta-
lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a
crystallographic study at 1.85-A resolution. Biochemistry. 1998 May
12;37(19):6791-800.2: Grady JK, Chasteen ND, Harris DC. Radicals from “Good’s” buffers. Anal
Biochem. 1988 Aug 15;173(1):111-5.3: Mönch S, Rychlik M. Improved folate extraction and tracing deconjugation
efficiency by dual label isotope dilution assays in foods. J Agric Food Chem.
2012 Feb 15;60(6):1363-72.

4: Syvertsen C, McKinley-McKee JS. Affinity labelling of liver alcohol
dehydrogenase. Effects of pH and buffers on affinity labelling with iodoacetic
acid and (R, S)-2-bromo-3-(5-imidazolyl)propionic acid. Eur J Biochem. 1981

5: Mönch S, Netzel M, Netzel G, Rychlik M. Quantitation of folates and their
catabolites in blood plasma, erythrocytes, and urine by stable isotope dilution
assays. Anal Biochem. 2010 Mar 15;398(2):150-60.

6: Lee KJ, Johnson N, Castelo J, Sinko PJ, Grass G, Holme K, Lee YH. Effect of
experimental pH on the in vitro permeability in intact rabbit intestines and
Caco-2 monolayer. Eur J Pharm Sci. 2005 Jun;25(2-3):193-200.

7: Jones JB, Trowbridge CG. A calorimetric investigation of the binding of
indole and phenylethane boronic acid to chymotrypsin. J Biol Chem. 1983 Feb

Products Realted to Tris Buffer pH 7 Biochemical Buffers and Solutions

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