Human Lys-Plasminogen

Product Description

Human Lys-Plasminogen
Catalog number: B2014393
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 83 kDa
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Human Lys-Plasminogen
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chen LY, Mehta JL. Lys- and glu-plasminogen potentiate the inhibitory effect of recombinant tissue plasminogen activator on human platelet aggregation Thromb Res. 1994 Jun 15;74(6):555-63.
2: Auer W, Muchitsch EM, Philapitsch A, Pichler L, Schwarz HP. Studies on the effect of human lys-plasminogen in a rat model of global cerebral ischemia Arzneimittelforschung. 1997 Nov;47(11):1195-9.
3: Fredenburgh JC, Nesheim ME. Lys-plasminogen is a significant intermediate in the activation of Glu-plasminogen during fibrinolysis in vitro J Biol Chem. 1992 Dec 25;267(36):26150-6.
4: Tykhomyrov AA, Zhernosekov DD, Roka-Moya YM, Diordieva SI, Grinenko TV. [THE EFFECTS OF LYS-PLASMINOGEN ON HUMAN PLATELET SECRETION] Fiziol Zh (1994). 2015;61(6):26-34.
5: Silverstein RL, Friedlander RJ Jr, Nicholas RL, Nachman RL. Binding of Lys-plasminogen to monocytes/macrophages J Clin Invest. 1988 Dec;82(6):1948-55.
6: Romagnuolo R, DeMarco K, Scipione CA, Boffa MB, Koschinsky ML. Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells Thromb Res. 2018 Sep;169:1-7.
7: Miles LA, Castellino FJ, Gong Y. Critical role for conversion of glu-plasminogen to Lys-plasminogen for optimal stimulation of plasminogen activation on cell surfaces Trends Cardiovasc Med. 2003 Jan;13(1):21-30.
8: Ito N, Noguchi K, Kazama M, Shimura K, Kasai K. Separation of human Glu-plasminogen, Lys-plasminogen and plasmin by high-performance affinity chromatography on Asahipak GS gel coupled with p-aminobenzamidine J Chromatogr. 1985 Nov 27;348(1):199-204.
9: Novokhatny VV, Kudinov SA, Privalov PL. Domains in human plasminogen J Mol Biol. 1984 Oct 25;179(2):215-32.
10: Zhang L, Gong Y, Grella DK, Castellino FJ, Miles LA. Endogenous plasmin converts Glu-plasminogen to Lys-plasminogen on the monocytoid cell surface J Thromb Haemost. 2003 Jun;1(6):1264-70.

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