DARC Antibody (Human)


Catalog Number: B2010533 (0.1 mg)
Human DARC Antibody is a highly pure mouse polyclonal antibody specific to the C-terminus of human Duffy antigen/chemokine receptor (DARC). This product has been used as versatile molecular tool in cellular biology. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human DARC Antibody
Catalog number: B2010533
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 150 kDa
Supplied as: Solution
Applications: versatile molecular tool in cellular biology
Storage: -20C
Keywords: DARC Antibody, Duffy antigen, Fy glycoprotein, GpFy, Cell adhesion molecule 3, CADM3, Anti-DARC Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Hadley TJ, Lu ZH, Wasniowska K, Martin AW, Peiper SC, Hesselgesser J, Horuk
R. Postcapillary venule endothelial cells in kidney express a multispecific
chemokine receptor that is structurally and functionally identical to the
erythroid isoform, which is the Duffy blood group antigen. J Clin Invest. 1994

2: Yamamoto A, Saito N, Ogasawara S, Shiratori T, Kondo J, Itoga M, Kayaba H.
Intracellular Storage of Duffy Antigen-Binding Chemokines by Duffy-Positive Red
Blood Cells. Clin Lab. 2017 Apr 1;63(4):717-723.

3: Du J, Luan J, Liu H, Daniel TO, Peiper S, Chen TS, Yu Y, Horton LW, Nanney
LB, Strieter RM, Richmond A. Potential role for Duffy antigen chemokine-binding
protein in angiogenesis and maintenance of homeostasis in response to stress. J
Leukoc Biol. 2002 Jan;71(1):141-53.

4: Estalote AC, Proto-Siqueira R, Silva WA Jr, Zago MA, Palatnik M. The mutation
G298A–>Ala100Thr on the coding sequence of the Duffy antigen/chemokine receptor
gene in non-caucasian Brazilians. Genet Mol Res. 2005 Jun 30;4(2):166-73.

5: Liu XH, Hadley TJ, Xu L, Peiper SC, Ray PE. Up-regulation of Duffy antigen
receptor expression in children with renal disease. Kidney Int. 1999

6: Ford A, Kepple D, Abagero BR, Connors J, Pearson R, Auburn S, Getachew S,
Ford C, Gunalan K, Miller LH, Janies DA, Rayner JC, Yan G, Yewhalaw D, Lo E.
Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence
and structural polymorphisms in erythrocyte binding genes. PLoS Negl Trop Dis.
2020 Oct 12;14(10):e0008234.

7: Allison AC. Genetic control of resistance to human malaria. Curr Opin
Immunol. 2009 Oct;21(5):499-505.

8: Horuk R, Wang ZX, Peiper SC, Hesselgesser J. Identification and
characterization of a promiscuous chemokine-binding protein in a human
erythroleukemic cell line. J Biol Chem. 1994 Jul 1;269(26):17730-3.

9: Malleret B, Rénia L, Russell B. The unhealthy attraction of Plasmodium vivax
to reticulocytes expressing transferrin receptor 1 (CD71). Int J Parasitol. 2017
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Riera-Borrull M, Sirvent JJ, Martín-Paredero V, Menendez JA, Camps J, Joven J.
Understanding the role of circulating chemokine (C-C motif) ligand 2 in patients
with chronic ischemia threatening the lower extremities. Vasc Med. 2014

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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