Human Alpha-2A Adrenergic Receptor

Product Description

Human Alpha-2A Adrenergic Receptor
Catalog number: B2016518
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 µg
Molecular Weight or Concentration: N/A
Supplied as: N/A
Applications: a molecular tool for various biochemical applications
Storage: N/A
Keywords: ADRA2, ADRAR, ALPHA2AAR
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Xu X, Wu G. Human C1orf27 protein interacts with α(2A)-adrenergic receptor and regulates its anterograde transport J Biol Chem. 2022 Jun;298(6):102021.
2: Chen Y, Peng Y, Che P, Gannon M, Liu Y, Li L, Bu G, van Groen T, Jiao K, Wang Q. α(2A) adrenergic receptor promotes amyloidogenesis through disrupting APP-SorLA interaction Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17296-301.
3: Kalapesi FB, Coroneo MT, Hill MA. Human ganglion cells express the alpha-2 adrenergic receptor: relevance to neuroprotection Br J Ophthalmol. 2005 Jun;89(6):758-63.
4: Fetterly TL, Basu A, Nabit BP, Awad E, Williford KM, Centanni SW, Matthews RT, Silberman Y, Winder DG. α(2A)-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity In Vivo J Neurosci. 2019 Jan 16;39(3):472-484.
5: Perez RE, Basu A, Nabit BP, Harris NA, Folkes OM, Patel S, Gilsbach R, Hein L, Winder DG. α(2A)-adrenergic heteroreceptors are required for stress-induced reinstatement of cocaine conditioned place preference Neuropsychopharmacology. 2020 Aug;45(9):1473-1481.
6: Dinter J, Mühlhaus J, Jacobi SF, Wienchol CL, Cöster M, Meister J, Hoefig CS, Müller A, Köhrle J, Grüters A, Krude H, Mittag J, Schöneberg T, Kleinau G, Biebermann H. 3-iodothyronamine differentially modulates α-2A-adrenergic receptor-mediated signaling J Mol Endocrinol. 2015 Jun;54(3):205-16.
7: Dorn GW 2nd, Oswald KJ, McCluskey TS, Kuhel DG, Liggett SB. Alpha 2A-adrenergic receptor stimulated calcium release is transduced by Gi-associated G(beta gamma)-mediated activation of phospholipase C Biochemistry. 1997 May 27;36(21):6415-23.
8: Kanagy NL. Alpha(2)-adrenergic receptor signalling in hypertension Clin Sci (Lond). 2005 Nov;109(5):431-7.
9: Choi YJ, Park KH, Park JY, Min WK, Lee YS. The effect of alpha-2A adrenergic receptor (ADRA2A) genetic polymorphisms on the depth of sedation of dexmedetomidine: a genetic observational pilot study Braz J Anesthesiol. 2022 Mar-Apr;72(2):241-246.
10: Yabe M, Matsubara Y, Takahashi S, Ishihara H, Shibano T, Watanabe G, Murata M, Ikeda Y. Alpha 2A adrenergic receptor polymorphism is associated with plasma von Willebrand factor levels in a general population Blood Coagul Fibrinolysis. 2008 Jul;19(5):395-9.

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