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Cyclin-Dependent Kinase 5 Human

Original price was: $2,795.00.Current price is: $1,395.00.

Catalog Number: B2016649 (1 vial)
Cyclin-Dependent Kinase 5 Human is a high quality protein that plays a crucial role in regulating cell cycle progression, neuronal migration, and synaptic function in humans. It is a member of the cyclin-dependent kinase family, which are enzymes that control the progression of the cell cycle by adding phosphate groups to other proteins. CDK5 is particularly important in the development and function of the nervous system, where it is involved in processes such as neuronal migration, synaptic plasticity, and neurodegeneration. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Cyclin-Dependent Kinase 5 Human
Catalog number: B2016649
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 vial
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: −80°C
Keywords: Cyclin-Dependent Kinase 5 Human
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tiwari MN, Hall BE, Ton AT, Ghetti R, Terse A, Amin N, Chung MK, Kulkarni AB. Activation of cyclin-dependent kinase 5 broadens action potentials in human sensory neurons Mol Pain. 2023 Jan-Dec;19:17448069231218353.
2: Sharma S, Zhang T, Michowski W, Rebecca VW, Xiao M, Ferretti R, Suski JM, Bronson RT, Paulo JA, Frederick D, Fassl A, Boland GM, Geng Y, Lees JA, Medema RH, Herlyn M, Gygi SP, Sicinski P. Targeting the cyclin-dependent kinase 5 in metastatic melanoma Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8001-8012.
3: Shelton SB, Johnson GV. Cyclin-dependent kinase-5 in neurodegeneration J Neurochem. 2004 Mar;88(6):1313-26.
4: Gomez K, Vallecillo TGM, Moutal A, Perez-Miller S, Delgado-Lezama R, Felix R, Khanna R. The role of cyclin-dependent kinase 5 in neuropathic pain Pain. 2020 Dec;161(12):2674-2689.
5: Odemuyiwa SO, Ilarraza R, Davoine F, Logan MR, Shayeganpour A, Wu Y, Majaesic C, Adamko DJ, Moqbel R, Lacy P. Cyclin-dependent kinase 5 regulates degranulation in human eosinophils Immunology. 2015 Apr;144(4):641-8.
6: Paul S, Fatihi S, Sharma S, Kutum R, Fields R, Pant HC, Thukral L, Bk B. Cyclin-Dependent Kinase 5 Regulates cPLA2 Activity and Neuroinflammation in Parkinson’s Disease eNeuro. 2022 Nov 23;9(6):ENEURO.0180-22.2022.
7: Tang D, Wang JH. Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators Prog Cell Cycle Res. 1996;2:205-16.
8: Lampropoulou E, Logoviti I, Koutsioumpa M, Hatziapostolou M, Polytarchou C, Skandalis SS, Hellman U, Fousteris M, Nikolaropoulos S, Choleva E, Lamprou M, Skoura A, Megalooikonomou V, Papadimitriou E. Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration Sci Rep. 2018 Apr 12;8(1):5893.
9: Ye T, Fu AK, Ip NY. Cyclin-dependent kinase 5 in axon growth and regeneration Int Rev Neurobiol. 2012;105:91-115.
10: Sano H, Namekata K, Niki M, Semba K, Murao F, Harada T, Mitamura Y. Ocular expression of cyclin-dependent kinase 5 in patients with proliferative diabetic retinopathy J Diabetes Investig. 2022 Apr;13(4):628-637.

Products Related to Cyclin-Dependent Kinase 5 Human can be found at Enzymes

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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