Sale!

Caspase-3 Substrate II Fluorogenic

Original price was: $1,195.00.Current price is: $595.00.

Catalog Number: B2013850 (1 mg)
Caspase-3 Substrate II Fluorogenic is a high quality Fluorogenic CPP32/Apopain substrate. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

In stock

SKU: B2013850 Categories: , Tag:

Product Description

Caspase-3 Substrate II Fluorogenic
Catalog number: B2013850
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration:
675.64 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Caspase-3 Substrate II, Fluorogenic, Ac-DEVD-AMC
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Aboul-Soud MAM, Ennaji H, Kumar A, Alfhili MA, Bari A, Ahamed M, Chebaibi M, Bourhia M, Khallouki F, Alghamdi KM, Giesy JP. Antioxidant, Anti-Proliferative Activity and Chemical Fingerprinting of Centaurea calcitrapa against Breast Cancer Cells and Molecular Docking of Caspase-3 Antioxidants (Basel). 2022 Aug 3;11(8):1514.
2: Palumbo C, De Luca A, Rosato N, Forgione M, Rotili D, Caccuri AM. c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition J Transl Med. 2016 Feb 4;14:37.
3: Takahashi T, Ogo M, Hibino T. Partial purification and characterization of two distinct types of caspases from human epidermis J Invest Dermatol. 1998 Sep;111(3):367-72.
4: Weglarczyk K, Baran J, Zembala M, Pryjma J. Caspase-8 activation precedes alterations of mitochondrial membrane potential during monocyte apoptosis induced by phagocytosis and killing of Staphylococcus aureus Infect Immun. 2004 May;72(5):2590-7.
5: Eley A, Hosseinzadeh S, Hakimi H, Geary I, Pacey AA. Apoptosis of ejaculated human sperm is induced by co-incubation with Chlamydia trachomatis lipopolysaccharide Hum Reprod. 2005 Sep;20(9):2601-7.
6: Lossi L, Cocito C, Alasia S, Merighi A. Ex vivo imaging of active caspase 3 by a FRET-based molecular probe demonstrates the cellular dynamics and localization of the protease in cerebellar granule cells and its regulation by the apoptosis-inhibiting protein survivin Mol Neurodegener. 2016 Apr 28;11:34.
7: Nagy K, Petak I, Imre G, Barna G, Gezane-Csorba M, Sebestyen A, Houghton JA, Mihalik R, Kopper L. Proteasome inhibitors abolish cell death downstream of caspase activation during anti-microtubule drug-induced apoptosis in leukemia cells Anticancer Res. 2005 Sep-Oct;25(5):3321-6.
8: Ottenheijm CA, Heunks LM, Li YP, Jin B, Minnaard R, van Hees HW, Dekhuijzen PN. Activation of the ubiquitin-proteasome pathway in the diaphragm in chronic obstructive pulmonary disease Am J Respir Crit Care Med. 2006 Nov 1;174(9):997-1002.
9: Dudich E, Semenkova L, Dudich I, Gorbatova E, Tochtamisheva N, Tatulov E, Nikolaeva M, Sukhikh G. alpha-fetoprotein causes apoptosis in tumor cells via a pathway independent of CD95, TNFR1 and TNFR2 through activation of caspase-3-like proteases Eur J Biochem. 1999 Dec;266(3):750-61.
10: Martins LM, Mesner PW, Kottke TJ, Basi GS, Sinha S, Tung JS, Svingen PA, Madden BJ, Takahashi A, McCormick DJ, Earnshaw WC, Kaufmann SH. Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis Blood. 1997 Dec 1;90(11):4283-96.

Products Related to Caspase-3 Substrate II Fluorogenic can be found at Substrates

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

Several ways to order Molecular Depot products:

1- Order online using our website’s automated shopping cart and checkout system (available 24/7).

2- Order by email: info@moleculardepot.com (we accept electronic PO, available 24/7).

3- Order by Fax: 1-858-437-9884 (available 24/7).

4- Order by Phone: 1-858-900-3210 (available 24/7).

5- Order by Text/SMS: 1-858-900-3210 (available 24/7).