Biotinyl-ω-Agatoxin IVA

Product Description

Biotinyl-ω-Agatoxin IVA
Catalog number: MDP0287
CAS Number: 581-05-5
Sequence: Biotinyl-Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala (Disulfide bonds between Cys4-Cys20, Cys12-Cys25, Cys19-Cys36 and Cys27-Cys34)
Amount: 100 ug
Molecular Weight: 5428.4 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Sawamoto K, Álvarez González JV, Piechnik M, Otero FJ, Couce ML, Suzuki Y, Tomatsu S. Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management Int J Mol Sci. 2020 Feb 23;21(4):1517.
2: Regier DS, Oetgen M, Tanpaiboon P. Mucopolysaccharidosis Type IVA 2013 Jul 11 [updated 2021 Jun 17]. In: Adam MP, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.
3: Rush RB, Rush SW. Faricimab for Treatment-Resistant Diabetic Macular Edema Clin Ophthalmol. 2022 Aug 24;16:2797-2801.
4: Rush RB, Rush SW. Intravitreal Faricimab for Aflibercept-Resistant Neovascular Age-Related Macular Degeneration Clin Ophthalmol. 2022 Dec 9;16:4041-4046.
5: Haddley K. Elosulfase alfa Drugs Today (Barc). 2014 Jul;50(7):475-83.
6: Guo X, Ji J, Zhang J, Hou X, Fu X, Luo Y, Mei Z, Feng Z. Anti-inflammatory and osteoprotective effects of Chikusetsusaponin Ⅳa on rheumatoid arthritis via the JAK/STAT signaling pathway Phytomedicine. 2021 Dec;93:153801.
7: Ryu JH, Jung HJ, Konishi S, Kim HH, Park ZY, Kim JI. Structure-activity relationships of ω-Agatoxin IVA in lipid membranes Biochem Biophys Res Commun. 2017 Jan 1;482(1):170-175.
8: Elosulfase Alfa (Vimizim) Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Jul.
9: Lustig HS, Ahern KB, Greenberg DA. omega-agatoxin IVA and excitotoxicity in cortical neuronal cultures Neurosci Lett. 1996 Aug 2;213(2):142-4.
10: Mansvelder HD, Stoof JC, Kits KS. Dihydropyridine block of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive Ca2+ channels in rat pituitary melanotropic cells Eur J Pharmacol. 1996 Sep 12;311(2-3):293-304.

Products Related to Biotinyl-ω-Agatoxin IVA can be found at Peptides