7B2 (23-39) Peptide

Product Description

7B2 (23-39) Peptide
Catalog number: B2014815
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 1934.02
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: 7B2 (23-39) (Human, Rat, Mouse, Porcine)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Vieau D, Tougard C, Rosenbaum E, Lenne F, Bertagna X. The Secretory Granule Protein 7B2 is Secreted in Parallel with Proopiomelanocortin and its End-Products by the Mouse Corticotroph Tumour Cells AtT-20 J Neuroendocrinol. 1991 Jun 1;3(3):229-31.
2: Hacker GW, Bishop AE, Terenghi G, Varndell IM, Aghahowa J, Pollard K, Thurner J, Polak JM. Multiple peptide production and presence of general neuroendocrine markers detected in 12 cases of human phaeochromocytoma and in mammalian adrenal glands Virchows Arch A Pathol Anat Histopathol. 1988;412(5):399-411.
3: Lee SN, Lindberg I. 7B2 prevents unfolding and aggregation of prohormone convertase 2 Endocrinology. 2008 Aug;149(8):4116-27.
4: Zhu X, Lindberg I. 7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity J Cell Biol. 1995 Jun;129(6):1641-50.
5: Seidah NG, Benjannet S, Hamelin J, Mamarbachi AM, Basak A, Marcinkiewicz J, Mbikay M, Chrétien M, Marcinkiewicz M. The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1 Ann N Y Acad Sci. 1999 Oct 20;885:57-74.
6: Dasgupta I, Sanglas L, Enghild JJ, Lindberg I. The neuroendocrine protein 7B2 is intrinsically disordered Biochemistry. 2012 Sep 25;51(38):7456-64.
7: Benjannet S, Savaria D, Chrétien M, Seidah NG. 7B2 is a specific intracellular binding protein of the prohormone convertase PC2 J Neurochem. 1995 May;64(5):2303-11.
8: Ramos-Molina B, Lindberg I. Phosphorylation and Alternative Splicing of 7B2 Reduce Prohormone Convertase 2 Activation Mol Endocrinol. 2015 May;29(5):756-64.
9: Helwig M, Hoshino A, Berridge C, Lee SN, Lorenzen N, Otzen DE, Eriksen JL, Lindberg I. The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins J Biol Chem. 2013 Jan 11;288(2):1114-24.
10: Ayoubi TA, van Duijnhoven HL, van de Ven WJ, Jenks BG, Roubos EW, Martens GJ. The neuroendocrine polypeptide 7B2 is a precursor protein J Biol Chem. 1990 Sep 15;265(26):15644-7.

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