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6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2016486 (2 mg)
6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate is a high quality chemical compound commonly used in analytical chemistry for derivatization of amino acids and peptides. It is used to improve the detection and analysis of these compounds in various analytical techniques such as liquid chromatography and mass spectrometry. AQC reacts with primary and secondary amines to form stable and fluorescent derivatives, making it a valuable tool in bioanalytical research. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate
Catalog number: B2016486
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 mg
Molecular Weight or Concentration: 285.26 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: RT
Keywords: 2,5-Dioxopyrrolidin-1-yl quinolin-6-ylcarbamate; 6-Aminoquinoline N-succinimidyl ester
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Masuda A, Dohmae N. Amino acid analysis of sub-picomolar amounts of proteins by precolumn fluorescence derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate Biosci Trends. 2011 Dec;5(6):231-8.
2: Li F, Karongo R, Mavridou D, Horak J, Sievers-Engler A, Lämmerhofer M. Automated sample preparation with 6-Aminoquinolyl-N-hydroxysuccinimidyl_carbamate and iodoacetamide derivatization reagents for enantioselective liquid chromatography tandem mass spectrometry amino acid analysis J Chromatogr A. 2023 Oct 11;1708:464349.
3: Mesonzhnik NV, Kuznetsov RM, Bochkareva NL, Appolonova SA. Application of 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatization for enhanced peptide mapping analysis of non-biological complex drug glatiramer acetate using liquid chromatography/electrospray ionization collision-induced dissociation high-resolution mass spectrometry Rapid Commun Mass Spectrom. 2020 May 15;34(9):e8748.
4: Horak J, Lämmerhofer M. Racemization without deamidation: Effect of racemization conditions on 6-aminoquinolyl-N-hydroxysuccinimidyl_carbamate tagged amino acids J Chromatogr A. 2019 Oct 25;1604:460492.
5: Ummiti K, Kumar JVS. Determination of Amino Acid Composition of Ganirelix Acetate in an Injectable Formulation by Pre-column Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl_Carbamate J Chromatogr Sci. 2020 Aug 21;58(8):687-694.
6: Horak J, Lämmerhofer M. Stereoselective separation of underivatized and 6-aminoquinolyl-N-hydroxysuccinimidyl_carbamate derivatized amino acids using zwitterionic quinine and quinidine type stationary phases by liquid chromatography-High resolution mass spectrometry J Chromatogr A. 2019 Jul 5;1596:69-78.
7: Wu Y, Sha Q, Du J, Wang C, Zhang L, Liu BF, Lin Y, Liu X. Determination of N-glycans by high performance liquid chromatography using 6-aminoquinolyl-N-hydroxysuccinimidyl_carbamate as the glycosylamine labeling reagent J Chromatogr A. 2018 Feb 2;1535:114-122.
8: Glover WB, Cohen SA, Murch SJ. Liquid chromatography and mass spectrometry for the analysis of N-β-methylamino-L-alanine with 6-aminoquinolyl-N-hydroxysuccinimidyl_carbamate Methods Mol Biol. 2015;1208:379-91.
9: Azilawati MI, Hashim DM, Jamilah B, Amin I. RP-HPLC method using 6-aminoquinolyl-N-hydroxysuccinimidyl_carbamate incorporated with normalization technique in principal component analysis to differentiate the bovine, porcine and fish gelatins Food Chem. 2015 Apr 1;172:368-76.
10: Pawlowska M, Chen S, Armstrong DW. Enantiomeric separation of fluorescent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, tagged amino acids J Chromatogr. 1993 Jul 9;641(2):257-65.

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Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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