3BP2 Fusion Protein

Product Description

3BP2 Fusion Protein
Catalog number: B2015542
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 μg
Molecular Weight or Concentration: 26 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: RT
Keywords: 3BP2; CRBM; CRPM; FLJ42079; FLJ54978; RES4-23
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Foucault I, Liu YC, Bernard A, Deckert M. The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function J Biol Chem. 2003 Feb 28;278(9):7146-53.
2: Foucault I, Le Bras S, Charvet C, Moon C, Altman A, Deckert M. The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor Blood. 2005 Feb 1;105(3):1106-13.
3: Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav Mol Cell Biol. 1994 Apr;14(4):2777-85.
4: Kapeller R, Prasad KV, Janssen O, Hou W, Schaffhausen BS, Rudd CE, Cantley LC. Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase J Biol Chem. 1994 Jan 21;269(3):1927-33.
5: Bouillie S, Barel M, Frade R. Signaling through the EBV/C3d receptor (CR2, CD21) in human B lymphocytes: activation of phosphatidylinositol 3-kinase via a CD19-independent pathway J Immunol. 1999 Jan 1;162(1):136-43.
6: Luci C, Vieira E, Bourinet M, Rousseau D, Bonnafous S, Patouraux S, Lefevre L, Larbret F, Prod’homme V, Iannelli A, Tran A, Anty R, Bailly-Maitre B, Deckert M, Gual P. SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic Steatohepatitis Cell Mol Gastroenterol Hepatol. 2022;13(1):173-191.
7: Hatani T, Sada K. Adaptor protein 3BP2 and cherubism Curr Med Chem. 2008;15(6):549-54.
8: Chihara K, Chihara Y, Takeuchi K, Sada K. Adaptor protein 3BP2 regulates dectin-1-mediated cellular signalling to induce cytokine expression and NF-κB activation Biochem J. 2022 Feb 17;479(4):503-523.
9: Deckert M, Rottapel R. The adapter 3BP2: how it plugs into leukocyte signaling Adv Exp Med Biol. 2006;584:107-14.
10: Deckert M. [The adaptor protein 3BP2 in leukocyte signaling] Med Sci (Paris). 2006 Dec;22(12):1081-6.

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