Parathyroid Hormone (Human, 1-31 Amide)

Product Description

Parathyroid Hormone (Human, 1-31 Amide)
Catalog number: MDP0692
CAS Number: N/A
Sequence: Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-NH2
Amount: 500 ug
Molecular Weight: 3718 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Chen Z, Xu P, Barbier JR, Willick G, Ni F. Solution structure of the osteogenic 1-31 fragment of the human parathyroid hormone Biochemistry. 2000 Oct 24;39(42):12766-77.
2: Fraher LJ, Avram R, Watson PH, Hendy GN, Henderson JE, Chong KL, Goltzman D, Morley P, Willick GE, Whitfield JF, Hodsman AB. Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans J Clin Endocrinol Metab. 1999 Aug;84(8):2739-43.
3: Singh AT, Kunnel JG, Strieleman PJ, Stern PH. Parathyroid hormone (PTH)-(1-34), [Nle(8,18),Tyr34]PTH-(3-34) amide, PTH-(1-31) amide, and PTH-related peptide-(1-34) stimulate phosphatidylcholine hydrolysis in UMR-106 osteoblastic cells: comparison with effects of phorbol 12,13-dibutyrate Endocrinology. 1999 Jan;140(1):131-7.
4: Henriksen K, Andersen JR, Riis BJ, Mehta N, Tavakkol R, Alexandersen P, Byrjalsen I, Valter I, Nedergaard BS, Teglbjaerg CS, Stern W, Sturmer A, Mitta S, Nino AJ, Fitzpatrick LA, Christiansen C, Karsdal MA. Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH(2)] in postmenopausal women with osteoporosis Bone. 2013 Mar;53(1):160-6.
5: Whitfield JF, Morley P, Willick GE, Ross V, Langille R, MacLean S, Barbier J, Isaacs RJ, Ohannessian-Barry L. Comparison of the abilities of human parathyroid hormone(1-31)NH2 and human parathyroid hormone-related protein(1-31)NH2 to stimulate femoral trabecular bone growth in ovariectomized rats Calcif Tissue Int. 1997 Oct;61(4):322-6.
6: Whitfield JF, Morley P, Willick G, Langille R, Ross V, MacLean S, Barbier JR. Cyclization by a specific lactam increases the ability of human parathyroid hormone (hPTH)-(1-31)NH2 to stimulate bone growth in ovariectomized rats J Bone Miner Res. 1997 Aug;12(8):1246-52.
7: Whitfield JF, Morley P, Willick GE, Ross V, MacLean S, Barbier JR, Isaacs RJ, Ohannessian-Barry L. Comparison of the ability of recombinant human parathyroid hormone, rhPTH-(1-84), and hPTH-(1-31)NH2 to stimulate femoral trabecular bone growth in ovariectomized rats Calcif Tissue Int. 1997 Jan;60(1):26-9.
8: Morley P, Whitfield JF, Willick GE, Ross V, MacLean S, Barbier JR, Isaacs RJ, Andreassen TT. The effect of monocyclic and bicyclic analogs of human parathyroid hormone (hPTH)-(1-31)NH2 on bone formation and mechanical strength in ovariectomized rats Calcif Tissue Int. 2001 Feb;68(2):95-101.
9: Whitfield JF, Morley P, Willick GE, MacLean S, Ross V, Barbier J, Isaacs RJ. Stimulation of femoral trabecular bone growth in ovariectomized rats by human parathyroid hormone (hPTH)-(1-30)NH(2) Calcif Tissue Int. 1999 Aug;65(2):143-7.
10: Whitfield JF, Isaacs R, MacLean S, Morley P, Barbier JR, Willick GE. Stimulation of membrane-associated protein kinase-C activity in spleen lymphocytes by hPTH-(1-31)NH2, its lactam derivative, [Leu27]-cyclo(Glu22-Lys26)-hPTH-(1-31)NH2, and hPTH-(1-30)NH2 Cell Signal. 1999 Mar;11(3):159-64.

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