Human Antimicrobial Peptide

Product Description

Human Antimicrobial Peptide
Catalog number: B2012953
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 ug
Molecular Weight or Concentration: N/A
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: LL-37
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wang G, Narayana JL, Mishra B, Zhang Y, Wang F, Wang C, Zarena D, Lushnikova T, Wang X. Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37 Adv Exp Med Biol. 2019;1117:215-240.
2: Aloul KM, Nielsen JE, Defensor EB, Lin JS, Fortkort JA, Shamloo M, Cirillo JD, Gombart AF, Barron AE. Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis Front Immunol. 2022 May 12;13:880961.
3: Chen X, Zou X, Qi G, Tang Y, Guo Y, Si J, Liang L. Roles and Mechanisms of Human Cathelicidin LL-37 in Cancer Cell Physiol Biochem. 2018;47(3):1060-1073.
4: Chen X, Deng S, Wang W, Castiglione S, Duan Z, Luo L, Cianci F, Zhang X, Xu J, Li H, Zhao J, Kamau PM, Zhang Z, Mwangi J, Li J, Shu Y, Hu X, Mazzanti M, Lai R. Human antimicrobial peptide LL-37 contributes to Alzheimer’s disease progression Mol Psychiatry. 2022 Nov;27(11):4790-4799.
5: Vera-Cruz A, Tanphaichitr N, Angel JB. Antimicrobial Peptide, LL-37, And Its Potential As An Anti-HIV Agent Clin Invest Med. 2021 Oct 3;44(3):E64-71.
6: Suzuki K, Ohkuma M, Someya A, Mita T, Nagaoka I. Human Cathelicidin Peptide LL-37 Induces Cell Death in Autophagy-Dysfunctional Endothelial Cells J Immunol. 2022 May 1;208(9):2163-2172.
7: Engelberg Y, Landau M. The Human LL-37(17-29) antimicrobial peptide reveals a functional supramolecular structure Nat Commun. 2020 Aug 4;11(1):3894.
8: Fabisiak A, Murawska N, Fichna J. LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity Pharmacol Rep. 2016 Aug;68(4):802-8.
9: Oliveira PN, Courrol DS, Chura-Chambi RM, Morganti L, Souza GO, Franzolin MR, Wunder EA Jr, Heinemann MB, Barbosa AS. Inactivation of the antimicrobial peptide LL-37 by pathogenic Leptospira Microb Pathog. 2021 Jan;150:104704.
10: Aidoukovitch A, Dahl S, Fält F, Nebel D, Svensson D, Tufvesson E, Nilsson BO. Antimicrobial peptide LL-37 and its pro-form, hCAP18, in desquamated epithelial cells of human whole saliva Eur J Oral Sci. 2020 Feb;128(1):1-6.

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