Glycogen Synthase Peptide-2

Product Description

Glycogen Synthase Peptide-2
Catalog number: B2014625
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 μg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Glycogen Synthase Peptide-2 (Ala21)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Yusta B, Estall J, Drucker DJ. Glucagon-like peptide-2 receptor activation engages bad and glycogen synthase kinase-3 in a protein kinase A-dependent manner and prevents apoptosis following inhibition of phosphatidylinositol 3-kinase J Biol Chem. 2002 Jul 12;277(28):24896-906.
2: Burrin DG, Stoll B, Guan X, Cui L, Chang X, Holst JJ. Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets Endocrinology. 2005 Jan;146(1):22-32.
3: Penna C, Pasqua T, Perrelli MG, Pagliaro P, Cerra MC, Angelone T. Postconditioning with glucagon like peptide-2 reduces ischemia/reperfusion injury in isolated rat hearts: role of survival kinases and mitochondrial KATP channels Basic Res Cardiol. 2012 Jul;107(4):272.
4: Dubé PE, Rowland KJ, Brubaker PL. Glucagon-like peptide-2 activates beta-catenin signaling in the mouse intestinal crypt: role of insulin-like growth factor-I Endocrinology. 2008 Jan;149(1):291-301.
5: Dozza B, Smith MA, Perry G, Tabaton M, Strocchi P. Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells J Neurochem. 2004 Jun;89(5):1224-32.
6: Papasozomenos SCh, Shanavas A. Testosterone prevents the heat shock-induced overactivation of glycogen synthase kinase-3 beta but not of cyclin-dependent kinase 5 and c-Jun NH2-terminal kinase and concomitantly abolishes hyperphosphorylation of tau: implications for Alzheimer’s disease Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1140-5.
7: Burrin DG, Stoll B, Guan X, Cui L, Chang X, Hadsell D. GLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E281-91.
8: Lawrence JC Jr, Skurat AV, Roach PJ, Azpiazu I, Manchester J. Glycogen synthase: activation by insulin and effect of transgenic overexpression in skeletal muscle Biochem Soc Trans. 1997 Feb;25(1):14-9.
9: Shimomura H, Sanke T. [Glycogen synthase gene] Nihon Rinsho. 1997 Oct;55 Suppl:442-5.
10: Beck-Nielsen H. The role of glycogen synthase in the development of hyperglycemia in type 2 diabetes: ‘To store or not to store glucose, that’s the question’ Diabetes Metab Res Rev. 2012 Nov;28(8):635-44.

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