CNTF Mimetic P6 Peptide


Catalog Number: B2014718 (5 mg)
CNTF Mimetic P6 Peptide is a high quality a brain-penetrating 11 residues peptide derived from the human ciliary neurotrophic factor (CTNF; residues 146-156) . This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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CNTF Mimetic P6 Peptide
Catalog number: B2014718
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 1203.39 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: CNTF Mimetic, P6 Peptide
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Kazim SF, Cardenas-Aguayo Mdel C, Arif M, Blanchard J, Fayyaz F, Grundke-Iqbal I, Iqbal K. Sera from children with autism induce autistic features which can be rescued with a CNTF small peptide mimetic in rats PLoS One. 2015 Mar 13;10(3):e0118627.
2: Kazim SF, Iqbal K. Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer’s disease Mol Neurodegener. 2016 Jul 11;11(1):50.
3: Simonyi G, Pados G, Medvegy M, Bedros JR. [The pharmacological treatment of obesity: past, present and future] Orv Hetil. 2012 Mar 11;153(10):363-73.
4: Daly C, Shine L, Heffernan T, Deeti S, Reynolds AL, O’Connor JJ, Dillon ET, Duffy DJ, Kolch W, Cagney G, Kennedy BN. A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model Sci Rep. 2017 Sep 12;7(1):11320.
5: Mattson MP, Duan W, Guo Z. Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms J Neurochem. 2003 Feb;84(3):417-31.
6: Safahani M, Aligholi H, Noorbakhsh F, Djalali M, Pishva H, Modarres Mousavi SM, Alizadeh L, Gorji A, Koohdani F. Switching from high-fat diet to foods containing resveratrol as a calorie restriction mimetic changes the architecture of arcuate nucleus to produce more newborn anorexigenic neurons Eur J Nutr. 2019 Jun;58(4):1687-1701.
7: Katoh M, Katoh M. STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review) Int J Mol Med. 2007 Feb;19(2):273-8.
8: Kazim SF, Blanchard J, Bianchi R, Iqbal K. Early neurotrophic pharmacotherapy rescues developmental delay and Alzheimer’s-like memory deficits in the Ts65Dn mouse model of Down syndrome Sci Rep. 2017 Apr 3;7:45561.
9: Wei W, Liu Y, Dai CL, Baazaoui N, Tung YC, Liu F, Iqbal K. Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction J Alzheimers Dis. 2021;82(2):631-646.
10: Russmann V, Seeger N, Zellinger C, Hadamitzky M, Pankratova S, Wendt H, Bock E, Berezin V, Potschka H. The CNTF-derived peptide mimetic Cintrofin attenuates spatial-learning deficits in a rat post-status epilepticus model Neurosci Lett. 2013 Nov 27;556:170-5.

Products Related to CNTF Mimetic P6 Peptide can be found at Peptides

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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