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Carbonic Anhydrase I from Human Erythrocytes

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2016607 (1 vial)
Carbonic Anhydrase I from Human Erythrocytes is a high quality enzyme found in human erythrocytes (red blood cells) that catalyzes the reversible hydration of carbon dioxide to form bicarbonate and protons. This enzyme plays a crucial role in maintaining the acid-base balance in the blood and facilitating the transport of carbon dioxide from the tissues to the lungs for elimination. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Carbonic Anhydrase I from Human Erythrocytes
Catalog number: B2016607
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 vial
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Carbonate Dehydratase, Carbonate Hydrolyase, Carbonic Anhydrase Isozyme I
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tunç T, Abdurrahmanoğlu S, Günel A, Alım Z, Demirel N. Influence of Chirality of Benzimidazole Amine Hybrids on Inhibition of Human Erythrocytes Carbonic Anhydrase I, II and Acetylcholinesterase Chem Biodivers. 2023 Jun;20(6):e202300207.
2: Alım Z, Köksal Z, Karaman M. Evaluation of some thiophene-based sulfonamides as potent inhibitors of carbonic anhydrase I and II isoenzymes isolated from human erythrocytes by kinetic and molecular modelling studies Pharmacol Rep. 2020 Dec;72(6):1738-1748.
3: Huyut Z, Beydemir Ş, Gülçin İ. Inhibition properties of some flavonoids on carbonic anhydrase I and II isoenzymes purified from human erythrocytes J Biochem Mol Toxicol. 2017 Sep;31(9).
4: Alim Z. 1H-indazole molecules reduced the activity of human erythrocytes carbonic anhydrase I and II isoenzymes J Biochem Mol Toxicol. 2018 Sep;32(9):e22194.
5: Argan O, Çıkrıkçı K, Baltacı A, Gencer N. The effects of cardiac drugs on human erythrocyte carbonic anhydrase I and II isozymes J Enzyme Inhib Med Chem. 2020 Dec;35(1):1359-1362.
6: Dilek E, Erol HS, Cakir A, Koc M, Halici MB. Natural product inhibitors of carbonic anhydrase I and II isoenzymes: osajin and pomiferin Arch Physiol Biochem. 2017 Oct;123(4):219-224.
7: Akıncıoğlu A, Göksu S, Naderi A, Akıncıoğlu H, Kılınç N, Gülçin İ. Cholinesterases, carbonic anhydrase inhibitory properties and in silico studies of novel substituted benzylamines derived from dihydrochalcones Comput Biol Chem. 2021 Oct;94:107565.
8: Villeval JL, Testa U, Vinci G, Tonthat H, Bettaieb A, Titeux M, Cramer P, Edelman L, Rochant H, Breton-Gorius J, et al. Carbonic anhydrase I is an early specific marker of normal human erythroid differentiation Blood. 1985 Nov;66(5):1162-70.
9: Ceylan M, Kocyigit UM, Usta NC, Gürbüzlü B, Temel Y, Alwasel SH, Gülçin İ. Synthesis, carbonic anhydrase I and II isoenzymes inhibition properties, and antibacterial activities of novel tetralone-based 1,4-benzothiazepine derivatives J Biochem Mol Toxicol. 2017 Apr;31(4).
10: Türkeş C, Demir Y, Beydemir Ş. Calcium channel blockers: molecular docking and inhibition studies on carbonic anhydrase I and II isoenzymes J Biomol Struct Dyn. 2021 Mar;39(5):1672-1680.

Products Related to Carbonic Anhydrase I from Human Erythrocytes can be found at Enzymes

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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