Anti-Perlecan Monoclonal Antibody

Product Description

Anti-Perlecan Monoclonal Antibody
Catalog number: B2014691
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 vial
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Anti-Perlecan Monoclonal Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chen LD, Hazlett LD. Perlecan in the basement membrane of corneal epithelium serves as a site for P. aeruginosa binding Curr Eye Res. 2000 Apr;20(4):260-7.
2: Groffen AJ, Ruegg MA, Dijkman H, van de Velden TJ, Buskens CA, van den Born J, Assmann KJ, Monnens LA, Veerkamp JH, van den Heuvel LP. Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane J Histochem Cytochem. 1998 Jan;46(1):19-27.
3: Hagen SG, Michael AF, Butkowski RJ. Immunochemical and biochemical evidence for distinct basement membrane heparan sulfate proteoglycans J Biol Chem. 1993 Apr 5;268(10):7261-9.
4: Groffen AJ, Hop FW, Tryggvason K, Dijkman H, Assmann KJ, Veerkamp JH, Monnens LA, Van den Heuvel LP. Evidence for the existence of multiple heparan sulfate proteoglycans in the human glomerular basement membrane and mesangial matrix Eur J Biochem. 1997 Jul 1;247(1):175-82.
5: Chen L, Hazlett LD. Human corneal epithelial extracellular matrix perlecan serves as a site for Pseudomonas aeruginosa binding Curr Eye Res. 2001 Jan;22(1):19-27.
6: Whitelock JM, Murdoch AD, Iozzo RV, Underwood PA. The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases J Biol Chem. 1996 Apr 26;271(17):10079-86.
7: Snow AD, Mar H, Nochlin D, Kimata K, Kato M, Suzuki S, Hassell J, Wight TN. The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer’s disease Am J Pathol. 1988 Dec;133(3):456-63.
8: Zhang J, Zhang QY, Fu YC, Wang T, Zhang J, Xu P, Zhou X, Pu PY, Kang CS. Expression of p-Akt and COX-2 in gastric adenocarcinomas and adenovirus mediated Akt1 and COX-2 ShRNA suppresses SGC-7901 gastric adenocarcinoma and U251 glioma cell growth in vitro and in vivo Technol Cancer Res Treat. 2009 Dec;8(6):467-78.
9: Castillo GM, Cummings JA, Ngo C, Yang W, Snow AD. Novel purification and detailed characterization of perlecan isolated from the Engelbreth-Holm-Swarm tumor for use in an animal model of fibrillar A beta amyloid persistence in brain J Biochem. 1996 Aug;120(2):433-44.
10: Kato M, Koike Y, Suzuki S, Kimata K. Basement membrane proteoglycan in various tissues: characterization using monoclonal antibodies to the Engelbreth-Holm-Swarm mouse tumor low density heparan sulfate proteoglycan J Cell Biol. 1988 Jun;106(6):2203-10.

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