COVID-19 infection and rheumatoid arthritis: Faraway, so close!

A new interesting article has been published in Autoimmun Rev. 2020 Mar 20:102523. doi: 10.1016/j.autrev.2020.102523. [Epub ahead of print] Review and titled:

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

Authors of this article are:

Favalli EG, Ingegnoli F, De Lucia O, Cincinelli G, Cimaz R, Caporali R.

A summary of the article is shown below:

The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has quickly become a global health emergency. Given the lack of specific anti-viral therapies, the current management of severe acute respiratory syndrome coronaviruses (SARS-CoV-2) is mainly supportive, even though several compounds are now under investigation for the treatment of this life-threatening disease. COVID-19 pandemic is certainly conditioning the treatment strategy of a complex disorder as rheumatoid arthritis (RA), whose infectious risk is increased compared to the general population because of an overall impairment of immune system typical of autoimmune diseases combined with the iatrogenic effect generated by corticosteroids and immunosuppressive drugs. However, the increasing knowledge about the pathophysiology of SARS-CoV-2 infection is leading to consider some anti-rheumatic drugs as potential treatment options for the management of COVID-19. In this review we will critically analyse the evidences on either positive or negative effect of drugs commonly used to treat RA in this particular scenario, in order to optimize the current approach to RA patients.Copyright © 2020. Published by Elsevier B.V.

Check out the article’s website on Pubmed for more information:

[link-preview url=https://www.ncbi.nlm.nih.gov/pubmed/32205186 forceshot=true]

This article is a good source of information and a good way to become familiar with topics such as: COVID-19; Coronavirus; Cytokine release syndrome; DMARDs; Rheumatoid arthritis; Treatment.


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