Blog

A new interesting article has been published in APMIS. 2019 Aug;127(8):570-576. doi: 10.1111/apm.12972. and titled:

Single-strain regression analysis evaluating disc potencies of flumequine and enrofloxacin for testing Aeromonas sobria and Vibrio anguillarum.

Authors of this article are:

Kronvall G, Baron S, Larvor E, Rudas-Villarreal C, Hobson J, Smith P.

A summary of the article is shown below:

Two quite different disc contents are used for antimicrobial susceptibility testing of two fluoroquinolone drugs, flumequine and enrofloxacin, in the disc diffusion test, 30 and 5 µg, respectively. Using the SRA method, single-strain regression analysis, we studied the impact of disc content when testing two relevant bacterial species, Aeromonas sobria and Vibrio anguillarum. There were no major differences between the antimicrobial regression lines for the two species. Wild-type strains produced acceptable zones of inhibition over a wide range of disc contents. The flumequine 30 µg disc should be lowered in its drug content. No rational reasons for choosing so different disc contents for the two antimicrobials were apparent. At present, the choice of disc content for new antimicrobials are outside the realm of clinical microbiologists. It is recommended that reference authorities, such as EUCAST, CLSI and USCAST, are consulted for the choice of disc contents in the future.© 2019 APMIS. Published by John Wiley & Sons Ltd.

Check out the article’s website on Pubmed for more information:

[link-preview url=https://www.ncbi.nlm.nih.gov/pubmed/31231825 forceshot=true]

This article is a good source of information and a good way to become familiar with topics such as: Aeromonas;Anti-Bacterial Agents;Enrofloxacin;Fluoroquinolones;Microbial Sensitivity Tests;Regression Analysis;Vibrio.

New Chemicals from MOLECULAR DEPOT

New Proteins from MOLECULAR DEPOT


New Antibodies from MOLECULAR DEPOT


New Research Kits from MOLECULAR DEPOT